Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases (Q21558502)

10.1371/JOURNAL.PONE.0027970

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Robert L Vessella

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Peter S Nelson

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Xiaotun Zhang

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Colm Morrissey

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17 November 2011

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10.1371/JOURNAL.PONE.0027970

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Tubulin-Targeting Chemotherapy Impairs Androgen Receptor Activity in Prostate Cancer

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

12 September 2017

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The expression of osteoclastogenesis-associated factors and osteoblast response to osteolytic prostate cancer cells

12 September 2017

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Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

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Protease-activated receptor-1 is upregulated in reactive stroma of primary prostate cancer and bone metastasis

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Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

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Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth

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Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases

12 September 2017

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Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells

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Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

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Androgen-independent induction of prostate-specific antigen gene expression via cross-talk between the androgen receptor and protein kinase A signal transduction pathways

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https://pubmed.ncbi.nlm.nih.gov/22114732

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An androgen-IL-6-Stat3 autocrine loop re-routes EGF signal in prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22114732

inferred from PubMed ID database lookup

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based on heuristic

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22114732

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0027970

1 reference

ADS bibcode

2011PLoSO...627970Z

0 references

1 reference

1 reference

1 reference