Polymerase (DNA directed), beta (Q21498319)

DNA polymerase lambda lyase domain superfamily

1 reference

DNA polymerase, thumb domain superfamily

1 reference

DNA polymerase beta, palm domain, protein family

1 reference

Helix-hairpin-helix DNA-binding motif, class 1, protein family

1 reference

DNA polymerase beta-like, N-terminal domain, protein family

1 reference

DNA polymerase beta, thumb domain, protein family

1 reference

DNA polymerase lambda, fingers domain, protein family

1 reference

DNA-directed DNA polymerase X family

1 reference

DNA polymerase family X, binding site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

1 reference

14 February 2019

lyase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

DNA-directed DNA polymerase activity

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

8 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

Normal immune function in young and old DNA polymerase-beta deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

DNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 reference

7 November 2018

DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

metal ion binding

ISO

DNA binding

5 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

DNA-directed DNA polymerase activity

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

Normal immune function in young and old DNA polymerase-beta deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

lyase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

5 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

DNA polymerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

1 reference

14 February 2019

protein binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

4 references

14 February 2019

ISS

14 February 2019

The murine DNA glycosylase NEIL2 (mNEIL2) and human DNA polymerase beta bind microtubules in situ and in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

synaptonemal complex

1 reference

14 February 2019

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

nucleus

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

nucleus

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

biological process

neuron apoptotic process

IGI

1 reference

14 February 2019

p53 Deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase beta-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

somatic hypermutation of immunoglobulin genes

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

homeostasis of number of cells

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

response to hyperoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

ageing

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

spleen development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

salivary gland morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

immunoglobulin heavy chain V-D-J recombination

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

1 reference

14 February 2019

somatic diversification of immunoglobulins

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

14 February 2019

Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

response to ethanol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

lymph node development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

response to gamma radiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

base-excision repair

Normal immune function in young and old DNA polymerase-beta deficient mice

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

base-excision repair, gap-filling

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

ISO

14 February 2019

Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

DNA biosynthetic process

DNA-dependent DNA replication

ISO

3 references

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K409&geneProductId=UniProtKB:Q8K409

base-excision repair

Normal immune function in young and old DNA polymerase-beta deficient mice

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

double-strand break repair via nonhomologous end joining

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

DNA biosynthetic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K409

1 reference

14 February 2019

DNA-directed DNA polymerase X

has part(s)

1 reference

DNA polymerase beta, palm domain

1 reference

Helix-hairpin-helix DNA-binding motif, class 1

1 reference

DNA polymerase lambda, fingers domain

1 reference

DNA polymerase family X, binding site

1 reference

DNA polymerase beta, thumb domain

1 reference

DNA polymerase beta-like, N-terminal domain

1 reference