One cut domain, family member 1 (Q21496448)

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mammalian protein found in Mus musculus

hepatocyte nuclear factor 6
HNF-3/forkhead homolog 12
hepatic nuclear factor 6
Onecut1
One cut domain family member 1
one cut homeobox 1

Language	Label	Description	Also known as
English	One cut domain, family member 1	mammalian protein found in Mus musculus	hepatocyte nuclear factor 6 HNF-3/forkhead homolog 12 hepatic nuclear factor 6 Onecut1 One cut domain family member 1 one cut homeobox 1

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Homeobox-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08755

Lambda repressor-like, DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08755

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CUT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

DNA-binding transcription factor activity

determination method or standard

1 reference

14 February 2019

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

1 reference

10 September 2018

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

determination method or standard

5 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

Plasticity and expanding complexity of the hepatic transcription factor network during liver development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

OC-3, a novel mammalian member of the ONECUT class of transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

determination method or standard

1 reference

10 September 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

determination method or standard

6 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

OC-3, a novel mammalian member of the ONECUT class of transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

Plasticity and expanding complexity of the hepatic transcription factor network during liver development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

3 references

7 November 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

7 November 2018

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

determination method or standard

4 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

24 April 2018

GDF11 modulates NGN3 islet progenitor cell number and promotes beta-cell differentiation in pancreas development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

determination method or standard

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

GDF11 modulates NGN3 islet progenitor cell number and promotes beta-cell differentiation in pancreas development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

biological process

Notch signaling pathway

determination method or standard

1 reference

14 February 2019

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

epithelial cell development

determination method or standard

1 reference

14 February 2019

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

cell differentiation

determination method or standard

1 reference

24 April 2018

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

cell fate commitment

determination method or standard

1 reference

14 February 2019

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

endoderm development

determination method or standard

1 reference

14 February 2019

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

positive regulation of cell migration

determination method or standard

1 reference

14 February 2019

The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

14 February 2019

The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

anatomical structure morphogenesis

determination method or standard

1 reference

14 February 2019

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

negative regulation of transforming growth factor beta receptor signaling pathway

determination method or standard

1 reference

14 February 2019

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

spleen development

determination method or standard

1 reference

14 February 2019

The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

regulation of cell-matrix adhesion

determination method or standard

1 reference

14 February 2019

The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

pancreas development

determination method or standard

liver development

determination method or standard

1 reference

14 February 2019

The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

B cell differentiation

determination method or standard

1 reference

14 February 2019

The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08755&geneProductId=UniProtKB:O08755

determination method or standard

cilium assembly

determination method or standard

1 reference

14 February 2019

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

cell differentiation

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08755

determination method or standard

Homeobox domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08755

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08755

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000058020

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000058020

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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