P21 (RAC1) activated kinase 3 (Q21496235)

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mammalian protein found in Mus musculus

PAK-3
Pak3
serine/threonine-protein kinase PAK 3
p21 protein (Cdc42/Rac)-activated kinase 3
CDC42/RAC effector kinase PAK-B
beta-PAK
p21-activated kinase 3

Language	Label	Description	Also known as
English	P21 (RAC1) activated kinase 3	mammalian protein found in Mus musculus	PAK-3 Pak3 serine/threonine-protein kinase PAK 3 p21 protein (Cdc42/Rac)-activated kinase 3 CDC42/RAC effector kinase PAK-B beta-PAK p21-activated kinase 3

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

CRIB domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

Serine/threonine-protein kinase PAK2/3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

p21 activated kinase binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CRIB domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

p21-activated kinase 3, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

kinase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

catalytic activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

transferase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

SH3 domain binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

metal ion binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

MAP kinase kinase activity

determination method or standard

protein binding

determination method or standard

protein serine/threonine kinase activity

determination method or standard

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

protein kinase activity

determination method or standard

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

14 February 2019

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

postsynaptic density

determination method or standard

1 reference

14 February 2019

Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

glutamatergic synapse

determination method or standard

1 reference

14 February 2019

Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

biological process

cellular response to organic cyclic compound

determination method or standard

1 reference

14 February 2019

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

phosphorylation

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

dendrite development

determination method or standard

1 reference

14 February 2019

p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

dendritic spine development

determination method or standard

1 reference

14 February 2019

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

multicellular organism development

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

determination method or standard

1 reference

14 February 2019

p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

actin cytoskeleton organization

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61036&geneProductId=UniProtKB:Q61036

determination method or standard

regulation of actin filament polymerization

determination method or standard

determination method or standard

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

dendritic spine morphogenesis

determination method or standard

1 reference

14 February 2019

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

Rho protein signal transduction

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61036&geneProductId=UniProtKB:Q61036

determination method or standard

regulation of mitotic cell cycle

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61036&geneProductId=UniProtKB:Q61036

determination method or standard

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

signal transduction

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

stress-activated protein kinase signaling cascade

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

activation of protein kinase activity

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

regulation of MAPK cascade

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

regulation of axonogenesis

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

protein phosphorylation

determination method or standard

regulation of apoptotic process

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61036

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

p21 activated kinase binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

p21-activated kinase 3, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61036

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000033640

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000033640

ENSMUSP00000108484

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000108484

ENSMUSP00000108485

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000108485

ENSMUSP00000108486

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000108486

ENSMUSP00000108489

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000108489

ENSMUSP00000126562

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126562

ENSMUSP00000114352

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000114352

ENSMUSP00000118549

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118549

ENSMUSP00000118716

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118716

ENSMUSP00000119090

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000119090

PDB structure ID

1 reference

UniProt protein ID

10 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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