Kinesin family member 3A (Q21495177)

Kinesin-like protein

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

Kinesin motor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Kinesin motor domain, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

14 February 2019

spectrin binding

1 reference

14 February 2019

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

ATPase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

protein binding

11 references

14 February 2019

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Protein kinase KIS localizes to RNA granules and enhances local translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

intraciliary transport particle B binding

1 reference

14 February 2019

IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

microtubule binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

3 references

14 February 2019

14 February 2019

Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

protein phosphatase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

14 February 2019

intraciliary transport particle

1 reference

24 April 2018

IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

14 February 2019

TAS

centrosome

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

14 February 2019

microtubule cytoskeleton

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

cilium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

3 references

14 February 2019

14 February 2019

Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

photoreceptor connecting cilium

1 reference

14 February 2019

Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

spindle microtubule

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

neuron projection

1 reference

14 February 2019

Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

microtubule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

1 reference

21 June 2018

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

14 February 2019

centriole

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

14 February 2019

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

motile cilium

1 reference

14 February 2019

Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

kinesin complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

biological process

cilium assembly

6 references

21 June 2018

Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

21 June 2018

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

21 June 2018

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

21 June 2018

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

21 June 2018

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

21 June 2018

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28741&geneProductId=UniProtKB:P28741

inner ear receptor cell stereocilium organization

1 reference

14 February 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

kidney development

1 reference

14 February 2019

Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

positive regulation of epithelial cell proliferation

1 reference

14 February 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

dentate gyrus development

1 reference

14 February 2019

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

motile cilium assembly

1 reference

14 February 2019

Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

in utero embryonic development

IGI

1 reference

14 February 2019

Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

IGI

heart looping

1 reference

14 February 2019

Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

heart development

1 reference

14 February 2019

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

determination of left/right symmetry

cell projection organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

14 February 2019

neural tube development

1 reference

14 February 2019

Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

epidermal stem cell homeostasis

1 reference

14 February 2019

Role of epidermal primary cilia in the homeostasis of skin and hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

neural precursor cell proliferation

1 reference

14 February 2019

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

epidermis development

1 reference

14 February 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

smoothened signaling pathway

dorsal/ventral neural tube patterning

Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

dorsal/ventral pattern formation

IGI

1 reference

14 February 2019

Analysis of mouse embryonic patterning and morphogenesis by forward genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

anterior/posterior pattern specification

1 reference

14 February 2019

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

centriole-centriole cohesion

1 reference

14 February 2019

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

microtubule anchoring at centrosome

1 reference

14 February 2019

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

non-motile cilium assembly

1 reference

14 February 2019

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

axon guidance

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

anterograde axonal transport

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

cilium assembly

Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

protein transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

protein localization to cell junction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28741

1 reference

Kinesin motor domain, conserved site

1 reference