Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway (Q21260429)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16417634 AND SRC:MED&resulttype=core&format=json

15 January 2020

title

Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway (English)

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15 January 2020

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1 reference

1 reference

6

Nils Cordes

Nils

Cordes

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15 January 2020

10

Claus Belka

Claus

Belka

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15 January 2020

Daniel Habermehl

1

Daniel

Habermehl

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15 January 2020

Bernd Kammerer

2

Bernd

Kammerer

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15 January 2020

René Handrick

3

René

Handrick

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15 January 2020

Therese Eldh

4

Therese

Eldh

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15 January 2020

Charlotte Gruber

5

Charlotte

Gruber

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15 January 2020

Peter T Daniel

7

Peter T

Daniel

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15 January 2020

Ludwig Plasswilm

8

Ludwig

Plasswilm

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15 January 2020

Michael Bamberg

9

Michael

Bamberg

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15 January 2020

Verena Jendrossek

11

Verena

Jendrossek

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15 January 2020

language of work or name

English

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publication date

17 January 2006

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full work available at URL

15 January 2020

https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-6-14

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1186/[email protected]

published in

BMC Cancer

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15 January 2020

volume

6

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15 January 2020

issue

1

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page(s)

14

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15 January 2020

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1186/[email protected]

access restriction status

open access

1 reference

inferred from online access status

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CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants

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Guardians of cell death: the Bcl-2 family proteins

12 September 2017

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Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy

12 September 2017

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Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy

12 September 2017

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Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability

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Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion

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12 September 2017

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Induction of apoptosis in cultured Chinese hamster ovary cells by Ukrain and its synergistic action with etoposide.

12 September 2017

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Induced apoptosis in human prostate cancer cell line LNCaP by Ukrain

12 September 2017

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12 September 2017

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12 September 2017

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Chemical analyses of Ukrain, a semi-synthetic Chelidonium majus alkaloid derivative, fail to confirm its trimeric structure.

12 September 2017

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Ukrain(TM), a semisynthetic Chelidonium majus alkaloid derivative, acts by inhibition of tubulin polymerization in normal and malignant cell lines.

12 September 2017

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12 September 2017

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12 September 2017

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Selective inhibition of in vitro cell growth by the anti-tumour drug Ukrain

12 September 2017

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12 September 2017

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Involvement of protein kinase C-related anti-apoptosis signaling in radiation-induced apoptosis in murine thymic lymphoma(3SBH5) cells

27 September 2017

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Ukrain, an alkaloid thiophosphoric acid derivative of Chelidonium majus L. protects human fibroblasts but not human tumour cells in vitro against ionizing radiation

27 September 2017

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Bcl-2 overexpression protects human keratinocyte cells from Ukrain-induced apoptosis but not from G2/M arrest

27 September 2017

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Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF-κB Activation, IκBα Phosphorylation, and Degradation

27 September 2017

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Benzophenanthridine alkaloids of Chelidonium majus; II. Potent inhibitory action against the growth of human keratinocytes.

27 September 2017

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Molecular ordering of hypoxia-induced apoptosis: critical involvement of the mitochondrial death pathway in a FADD/caspase-8 independent manner

27 September 2017

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Intracellular mediators of erucylphosphocholine-induced apoptosis

30 May 2018

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Water extract isolated from Chelidonium majus enhances nitric oxide and tumour necrosis factor-alpha production via nuclear factor-kappaB activation in mouse peritoneal macrophages

21 January 2018

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21 January 2018

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Antitumor activity of protein kinase C inhibitors and cisplatin in human head and neck squamous cell carcinoma lines

21 January 2018

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The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death

21 January 2018

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Identification of chelerythrine as an inhibitor of BclXL function

21 January 2018

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Effect of Ukrain on the growth and metastasizing of Lewis carcinoma in C57BL/6 mice

21 January 2018

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29 November 2018

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29 November 2018

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Acute hepatitis induced by Greater Celandine (Chelidonium majus)

29 November 2018

1 reference

12 December 2020

Enhancement of macrophage tumouricidal activity by the alkaloid derivative Ukrain. In vitro and in vivo studies

1 reference

12 December 2020

Preliminary studies on the effect of Ukrain (Tris(2-([5bS-(5ba,6b,12ba)]- 5b,6,7,12b,13,14-hexahydro-13-methyl[1,3] benzodioxolo[5,6-v]-1-3- dioxolo[4,5-i]phenanthridinium-6-ol]-Ethaneaminyl)Phosphinesulfide.6HCl ) on the immunological response in p

1 reference

12 December 2020

The effects of thiophosphoric acid (Ukrain) on cervical cancer, stage IB bulky

1 reference

12 December 2020

Antimicrotubule properties of benzophenanthridine alkaloids

1 reference

12 December 2020

Induction of bimodal programmed cell death in malignant cells by the derivative Ukrain (NSC-631570)

1 reference

12 December 2020

Influence of Ukrain on human xenografts in vitro

1 reference

12 December 2020

Benzophenanthridine alkaloids of Chelidonium majus; I. Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism

1 reference

12 December 2020

Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation

1 reference

12 December 2020

Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum

1 reference

12 December 2020

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

1 reference

12 December 2020

Induced G2/M arrest and apoptosis in human epidermoid carcinoma cell lines by semisynthetic drug Ukrain

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-6-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16417634 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16417634 AND SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

16417634

1 reference