ADP ribosylation factor 1 (Q21201413)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P84077

Small GTPase superfamily, ARF/SAR type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P84077

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

phospholipase D activator activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

GTP binding

magnesium ion binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

GDP binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

protein binding

5 references

8 April 2019

Dissecting the role of the ARF guanine nucleotide exchange factor GBF1 in Golgi biogenesis and protein trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

RNA binding

1 reference

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

protein domain specific binding

1 reference

8 April 2019

Structure of the GAT domain of human GGA1: A syntaxin amino-terminal domain fold in an endosomal trafficking adaptor

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

protein heterodimerization activity

1 reference

8 April 2019

Structure of the GAT domain of human GGA1: A syntaxin amino-terminal domain fold in an endosomal trafficking adaptor

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

RNA binding

1 reference

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

GTP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

cell component

extracellular exosome

3 references

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

late endosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

1 reference

17 October 2017

synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

trans-Golgi network

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

endomembrane system

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

peroxisomal membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

cell leading edge

1 reference

8 April 2019

GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kγ activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

neuron projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

postsynaptic membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

focal adhesion

1 reference

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

intracellular anatomical structure

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

1 reference

17 October 2017

perinuclear region of cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

sarcomere

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

COPI-coated vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

plasma membrane

Evidence for ADP-ribosylation-factor-mediated activation of phospholipase D by m3 muscarinic acetylcholine receptor

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

focal adhesion

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

extracellular exosome

3 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

positive regulation of endocytosis

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

positive regulation of protein secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

very-low-density lipoprotein particle assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

mitigation of host defenses by virus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

positive regulation of calcium ion-dependent exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

synaptic vesicle budding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

small GTPase mediated signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

1 reference

17 October 2017

cellular copper ion homeostasis

1 reference

8 April 2019

The ADP-ribosylation factor 1 (Arf1) is involved in regulating copper uptake

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

antigen processing and presentation of exogenous peptide antigen via MHC class II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

Golgi to transport vesicle transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

post-Golgi vesicle-mediated transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

1 reference

17 October 2017

actin filament organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

lysosomal membrane organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

positive regulation of ER to Golgi vesicle-mediated transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

regulation of phospholipid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

positive regulation of late endosome to lysosome transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

phosphatidylinositol biosynthetic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

positive regulation of sodium ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

positive regulation of catalytic activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

positive regulation of dendritic spine development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

mitotic cleavage furrow ingression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

interleukin-12-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

1 reference

8 April 2019

transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P84077&geneProductId=UniProtKB:P84077

1 reference

17 October 2017

intracellular protein transport

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

Golgi to plasma membrane transport

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

vesicle-mediated transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

postsynaptic actin cytoskeleton organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P84077

small GTP-binding protein domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P84077

Identifiers

MeSH descriptor ID

D020823

subject named as

ADP-Ribosylation Factor 1

0 references

MeSH tree code

D08.811.277.040.330.300.400.100.100

0 references

D12.776.157.325.515.100.100

0 references

D12.776.476.338.400.100.100

0 references

D12.776.543.990.300.150

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023