Shugoshin 1 (Q21173507)

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mammalian protein found in Homo sapiens

shugoshin 1
shugoshin 1AB protein
serologically defined breast cancer antigen NY-BR-85
shugoshin 1KL protein
shugoshin-like 1
shugoshin 1GH protein
shugoshin 1CD protein
SGO1
shugoshin 1EF protein

Language	Label	Description	Also known as
English	Shugoshin 1	mammalian protein found in Homo sapiens	shugoshin 1 shugoshin 1AB protein serologically defined breast cancer antigen NY-BR-85 shugoshin 1KL protein shugoshin-like 1 shugoshin 1GH protein shugoshin 1CD protein SGO1 shugoshin 1EF protein

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5FBB7

Shugoshin, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Shugoshin, N-terminal coiled-coil domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

protein binding

determination method

11 references

8 April 2019

PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Heterochromatin links to centromeric protection by recruiting shugoshin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Shugoshin collaborates with protein phosphatase 2A to protect cohesin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

3 references

8 April 2019

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

microtubule organizing center

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

chromosome, centromeric region

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Phospho-H2A and cohesin specify distinct tension-regulated Sgo1 pools at kinetochores and inner centromeres

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

2 references

determination method

8 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Differential subcellular localizations of two human Sgo1 isoforms: implications in regulation of sister chromatid cohesion and microtubule dynamics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

condensed chromosome, centromeric region

determination method

1 reference

8 April 2019

A nucleolar protein RRS1 contributes to chromosome congression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

biological process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

attachment of spindle microtubules to kinetochore

determination method

1 reference

8 April 2019

Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

centriole-centriole cohesion

determination method

3 references

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

8 April 2019

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5FBB7

determination method

Shugoshin, N-terminal coiled-coil domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5FBB7

Shugoshin, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5FBB7

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000263753

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000263753

ENSP00000306581

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000306581

ENSP00000389034

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000389034

ENSP00000394613

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394613

ENSP00000394625

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394625

ENSP00000394957

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394957

ENSP00000410458

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000410458

ENSP00000411200

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411200

ENSP00000413070

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413070

ENSP00000414129

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000414129

ENSP00000414960

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000414960

ENSP00000397672

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397672

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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