junction plakoglobin (Q21139990)

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mammalian protein found in Homo sapiens
  • catenin (cadherin-associated protein), gamma 80kDa
  • JUP
  • desmoplakin-3
  • Catenin gamma
  • desmoplakin III
  • Junction plakoglobin
  • gamma catenin
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Language Label Description Also known as
English
junction plakoglobin
mammalian protein found in Homo sapiens
  • catenin (cadherin-associated protein), gamma 80kDa
  • JUP
  • desmoplakin-3
  • Catenin gamma
  • desmoplakin III
  • Junction plakoglobin
  • gamma catenin

Statements

molecular function
protein binding
determination method or standard
IPI
18 references
retrieved
8 April 2019
stated in
E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly
GOA
curator
UniProt
UniProt protein ID
P14923
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)
GOA
curator
UniProt
UniProt protein ID
P14923
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
A human MAP kinase interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
An empirical framework for binary interactome mapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
alpha-catenin binding
determination method or standard
IBA
IEA
IPI
6 references
retrieved
8 April 2019
stated in
Mutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathy
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IPI
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IBA
cell component
cell-cell junction
determination method or standard
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IEA
retrieved
8 April 2019
stated in
Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer
GOA
curator
UniProt
UniProt protein ID
P14923
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IDA
retrieved
8 April 2019
stated in
Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IDA
retrieved
8 April 2019
stated in
Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IDA
retrieved
8 April 2019
stated in
Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IDA
retrieved
8 April 2019
stated in
Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14923
determination method or standard
IDA
biological process

Identifiers

MeSH descriptor ID
D051185
subject named as
gamma Catenin
0 references
Freebase ID
/m/0h4bm4
0 references
Microsoft Academic ID
48220470
0 references
2909450770
0 references
 
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