thioredoxin reductase 2 (Q21125517)

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mammalian protein found in Homo sapiens

SelZ
TR-beta
TXNRD2
thioredoxin reductase 2, mitochondrial
selenoprotein Z
thioredoxin reductase TR3
thioredoxin reductase beta
thioredoxin reductase 3

Language	Label	Description	Also known as
English	thioredoxin reductase 2	mammalian protein found in Homo sapiens	SelZ TR-beta TXNRD2 thioredoxin reductase 2, mitochondrial selenoprotein Z thioredoxin reductase TR3 thioredoxin reductase beta thioredoxin reductase 3

Statements

1 reference

13 November 2019

UniProt protein ID

FAD/NAD-linked reductase, dimerisation domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNW7

Thioredoxin/glutathione reductase selenoprotein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNW7

FAD/NAD(P)-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNW7

FAD/NAD(P)-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pyridine nucleotide-disulphide oxidoreductase, class I, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method or standard

1 reference

8 April 2019

Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

flavin adenine dinucleotide binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

thioredoxin-disulfide reductase activity

determination method or standard

6 references

10 September 2018

Cloning, sequencing and functional expression of a novel human thioredoxin reductase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

10 September 2018

Reconstitution of the mitochondrial PrxIII antioxidant defence pathway: general properties and factors affecting PrxIII activity and oligomeric state

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

electron transfer activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

thioredoxin-disulfide reductase activity

determination method or standard

5 references

8 April 2019

Cloning, sequencing and functional expression of a novel human thioredoxin reductase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

mitochondrial matrix

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

determination method or standard

3 references

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

21 June 2018

Human mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

21 June 2018

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NNW7&geneProductId=UniProtKB:Q9NNW7

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

Human mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

biological process

response to oxygen radical

determination method or standard

1 reference

8 April 2019

Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

cellular oxidant detoxification

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

cellular response to oxidative stress

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

electron transport chain

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

cell redox homeostasis

determination method or standard

3 references

8 April 2019

Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NNW7

determination method or standard

Pyridine nucleotide-disulphide oxidoreductase, class I, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNW7

FAD/NAD(P)-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNW7

Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NNW7

Identifiers

MeSH descriptor ID

subject named as

Thioredoxin Reductase 2

0 references

D08.811.682.667.750.750

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000383369

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383369

ENSP00000383363

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383363

ENSP00000485128

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485128

ENSP00000485466

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485466

ENSP00000485603

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485603

ENSP00000485665

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485665

ENSP00000334451

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000334451

ENSP00000383362

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383362

ENSP00000383365

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383365

ENSP00000489208

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000489208

ENSP00000485543

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485543

ENSP00000485290

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485290

ENSP00000485499

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485499

PDB structure ID

1 reference

6 January 2016

http://www.uniprot.org/uniprot/Q9NNW7.txt?version=155

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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