Wnt family member 3 (Q21115930)

http://www.ebi.ac.uk/interpro/protein/P56703

Wnt protein, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

receptor ligand activity

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

protein domain specific binding

IC

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

frizzled binding

protein binding

2 references

1 January 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

signaling receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

frizzled binding

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

cell component

cytoplasm

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

endocytic vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

Wnt signalosome

endoplasmic reticulum lumen

IC

NAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

extracellular region

Golgi lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

extracellular exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

extracellular space

1 reference

21 June 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56703&geneProductId=UniProtKB:P56703

extracellular matrix

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

extracellular space

cellular response to retinoic acid

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 reference

1 January 2018

ISS

cell fate commitment

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

Spemann organizer formation at the anterior end of the primitive streak

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

head morphogenesis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

limb bud formation

1 reference

1 January 2018

Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

mammary gland epithelium development

IEP

1 reference

1 January 2018

Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

anatomical structure formation involved in morphogenesis

IEP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

mesoderm formation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

positive regulation of collateral sprouting in absence of injury

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

negative regulation of axon extension involved in axon guidance

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

dorsal/ventral axis specification

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

axon guidance

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

limb development

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

positive regulation of Wnt signaling pathway

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

gamete generation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation

1 reference

1 January 2018

Wnt3-frizzled 1 chimera as a model to study canonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

canonical Wnt signaling pathway involved in osteoblast differentiation

1 reference

1 January 2018

Wnt3-frizzled 1 chimera as a model to study canonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

cell morphogenesis

1 reference

1 January 2018

Wnt3 modulates the characteristics and cobblestone area-supporting activity of human stromal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

canonical Wnt signaling pathway

The regulation and deregulation of Wnt signaling by PARK genes in health and disease

6 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

Wnt3 modulates the characteristics and cobblestone area-supporting activity of human stromal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

anterior/posterior axis specification

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

embryonic forelimb morphogenesis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

anterior/posterior pattern specification

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

embryonic hindlimb morphogenesis

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

Wnt signaling pathway

regulation of neurogenesis

1 reference

1 January 2018

Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

stem cell proliferation

1 reference

1 January 2018

Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation

1 reference

1 January 2018

Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

canonical Wnt signaling pathway involved in stem cell proliferation

1 reference

1 January 2018

Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

neuron differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56703&geneProductId=UniProtKB:P56703

1 reference

21 June 2018

regulation of signaling receptor activity

ISS

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

1 January 2018

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56703

Wnt protein, conserved site

has part(s)

1 reference

InterPro Release 71.0