Protein tyrosine phosphatase non-receptor type 22 (Q21114040)

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mammalian protein found in Homo sapiens
  • protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
  • PEP
  • tyrosine-protein phosphatase non-receptor type 22
  • protein tyrosine phosphatase, non-receptor type 8
  • PEST-domain phosphatase
  • PTPN22
  • hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • LyP
  • Lymphoid phosphatase
  • lymphoid-specific protein tyrosine phosphatase
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Language Label Description Also known as
English
Protein tyrosine phosphatase non-receptor type 22
mammalian protein found in Homo sapiens
  • protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
  • PEP
  • tyrosine-protein phosphatase non-receptor type 22
  • protein tyrosine phosphatase, non-receptor type 8
  • PEST-domain phosphatase
  • PTPN22
  • hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • LyP
  • Lymphoid phosphatase
  • lymphoid-specific protein tyrosine phosphatase

Statements

molecular function
protein binding
determination method or standard
IPI
8 references
retrieved
8 April 2019
stated in
Large-scale structural analysis of the classical human protein tyrosine phosphatome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Proline-serine-threonine phosphatase interacting protein 1 inhibition of T-cell receptor signaling depends on its SH3 domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of substrates of human protein-tyrosine phosphatase PTPN22
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
retrieved
8 April 2019
stated in
Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IPI
protein tyrosine phosphatase activity
determination method or standard
IDA
IEA
TAS
6 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y2R2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IEA
retrieved
8 April 2019
stated in
Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases
GOA
curator
UniProt
UniProt protein ID
Q9Y2R2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IDA
retrieved
8 April 2019
stated in
Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IDA
retrieved
8 April 2019
stated in
Identification of substrates of human protein-tyrosine phosphatase PTPN22
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2R2
determination method or standard
IDA
cell component
biological process

Identifiers

 
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