CD6 molecule (Q21113034)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P30203

SRCR domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SRCR-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

lipopolysaccharide binding

1 reference

9 May 2019

CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

lipoteichoic acid binding

1 reference

9 May 2019

CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

scavenger receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

protein binding

3 references

9 May 2019

Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

9 May 2019

Modulation of CD6 function through interaction with Galectin-1 and -3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

9 May 2019

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

identical protein binding

1 reference

9 May 2019

Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

intrinsic component of plasma membrane

1 reference

9 May 2019

Relevance of CD6-mediated interactions in T cell activation and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

integral component of plasma membrane

TAS

1 reference

9 May 2019

The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

TAS

T cell receptor complex

1 reference

9 May 2019

Relevance of CD6-mediated interactions in T cell activation and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

immunological synapse

1 reference

9 May 2019

Relevance of CD6-mediated interactions in T cell activation and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

external side of plasma membrane

IBA

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

positive regulation of cytokine production involved in inflammatory response

IBA

biological process

1 reference

9 May 2019

CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

1 reference

9 May 2019

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

adaptive immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

acute inflammatory response to antigenic stimulus

1 reference

9 May 2019

CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

receptor-mediated endocytosis

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

response to lipopolysaccharide

1 reference

9 May 2019

CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

positive regulation of T cell proliferation

1 reference

9 May 2019

Relevance of CD6-mediated interactions in T cell activation and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

9 May 2019

immunological synapse formation

1 reference

9 May 2019

Relevance of CD6-mediated interactions in T cell activation and proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

lipopolysaccharide-mediated signaling pathway

1 reference

9 May 2019

CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

vesicle-mediated transport

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

endocytosis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30203

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P30203

SRCR domain

1 reference

InterPro Release 71.0