Biogenesis of lysosomal organelles complex 1 subunit 2 (Q21111716)

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mammalian protein found in Homo sapiens

biogenesis of lysosome-related organelles complex 1 subunit 2
11 kDa centrosome associated protein
BLOC-1 subunit 2
centrosomal 10 kDa protein
BLOC1S2
Centrosome-associated protein
centrosome protein oncogene

Language	Label	Description	Also known as
English	Biogenesis of lysosomal organelles complex 1 subunit 2	mammalian protein found in Homo sapiens	biogenesis of lysosome-related organelles complex 1 subunit 2 11 kDa centrosome associated protein BLOC-1 subunit 2 centrosomal 10 kDa protein BLOC1S2 Centrosome-associated protein centrosome protein oncogene

Statements

1 reference

13 November 2019

UniProt protein ID

Biogenesis of lysosome-related organelles complex-1, subunit 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6QNY1

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

7 references

8 April 2019

BORC, a multisubunit complex that regulates lysosome positioning.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

Ceap/BLOS2 interacts with BRD7 and selectively inhibits its transcription-suppressing effect on cellular proliferation-associated genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

gamma-tubulin binding

determination method

1 reference

27 March 2018

Characterization of Ceap-11 and Ceap-16, two novel splicing-variant-proteins, associated with centrosome, microtubule aggregation and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

protein C-terminus binding

determination method

1 reference

27 March 2018

Ceap/BLOS2 interacts with BRD7 and selectively inhibits its transcription-suppressing effect on cellular proliferation-associated genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

oxidoreductase activity

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

gamma-tubulin binding

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

3 references

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

27 March 2018

Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

27 March 2018

Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

gamma-tubulin complex

determination method

1 reference

27 March 2018

Characterization of Ceap-11 and Ceap-16, two novel splicing-variant-proteins, associated with centrosome, microtubule aggregation and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

microtubule organizing center

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

8 April 2019

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

27 March 2018

Ceap/BLOS2 interacts with BRD7 and selectively inhibits its transcription-suppressing effect on cellular proliferation-associated genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

27 March 2018

Characterization of Ceap-11 and Ceap-16, two novel splicing-variant-proteins, associated with centrosome, microtubule aggregation and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

lysosomal membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

determination method

1 reference

27 March 2018

BORC, a multisubunit complex that regulates lysosome positioning.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

gamma-tubulin complex

determination method

determination method

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

biological process

platelet dense granule organization

determination method

1 reference

8 April 2019

Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

27 March 2018

Ceap/BLOS2 interacts with BRD7 and selectively inhibits its transcription-suppressing effect on cellular proliferation-associated genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

melanosome organization

determination method

positive regulation of cell population proliferation

determination method

1 reference

27 March 2018

Characterization of Ceap-11 and Ceap-16, two novel splicing-variant-proteins, associated with centrosome, microtubule aggregation and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

neuron projection development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

mitochondrial outer membrane permeabilization

determination method

1 reference

8 April 2019

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

extrinsic apoptotic signaling pathway via death domain receptors

determination method

1 reference

8 April 2019

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

microtubule nucleation

determination method

1 reference

27 March 2018

Characterization of Ceap-11 and Ceap-16, two novel splicing-variant-proteins, associated with centrosome, microtubule aggregation and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

lysosome localization

determination method

1 reference

27 March 2018

BORC, a multisubunit complex that regulates lysosome positioning.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6QNY1&geneProductId=UniProtKB:Q6QNY1

determination method

endosomal transport

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6QNY1

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000359398

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359398

ENSP00000410865

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000410865

ENSP00000481847

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000481847

ENSP00000464387

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464387

ENSP00000484340

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484340

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Multilingual sites(0 entries)

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