CCR4-NOT transcription complex subunit 7 (Q21111282)

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mammalian protein found in Homo sapiens
  • CCR4-associated factor 1
  • CNOT7
  • carbon catabolite repressor protein (CCR4)-associative factor 1
  • CAF-1
  • Caf1a
  • BTG1-binding factor 1
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Language Label Description Also known as
English
CCR4-NOT transcription complex subunit 7
mammalian protein found in Homo sapiens
  • CCR4-associated factor 1
  • CNOT7
  • carbon catabolite repressor protein (CCR4)-associative factor 1
  • CAF-1
  • Caf1a
  • BTG1-binding factor 1

Statements

molecular function
protein binding
determination method or standard
IPI
20 references
retrieved
8 April 2019
stated in
MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
A directed protein interaction network for investigating intracellular signal transduction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of four families of yCCR4- and Mg2 -dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structural basis for the antiproliferative activity of the Tob-hCaf1 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
retrieved
8 April 2019
stated in
CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by tristetraprolin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IPI
poly(A)-specific ribonuclease activity
determination method or standard
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IEA
retrieved
8 April 2019
stated in
Structural basis for the antiproliferative activity of the Tob-hCaf1 complex
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IDA
retrieved
8 April 2019
stated in
Conservation of the deadenylase activity of proteins of the Caf1 family in human
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IDA
retrieved
8 April 2019
stated in
Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase
GOA
curator
UniProt
UniProt protein ID
Q9UIV1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIV1
determination method or standard
IBA
cell component
biological process

Identifiers

RefSeq protein ID
 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21111282&oldid=2022945082"