POU class 2 homeobox associating factor 1 (Q21109090)

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mammalian protein found in Homo sapiens

POU2AF1
POU class 2 associating factor 1
BOB-1
B-cell-specific coactivator OBF-1
OCA-B
POU domain class 2-associating factor 1
OCT-binding factor 1

Language	Label	Description	Also known as
English	POU class 2 homeobox associating factor 1	mammalian protein found in Homo sapiens	POU2AF1 POU class 2 associating factor 1 BOB-1 B-cell-specific coactivator OBF-1 OCA-B POU domain class 2-associating factor 1 OCT-binding factor 1

Statements

1 reference

13 November 2019

UniProt protein ID

POU, class 2, associating factor 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16633

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

transcription coactivator activity

determination method or standard

1 reference

24 April 2018

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Regulation of BOB.1/OBF.1 stability by SIAH

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

transcription coregulator activity

determination method or standard

1 reference

8 April 2019

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

RNA polymerase II core promoter sequence-specific DNA binding

determination method or standard

3 references

24 April 2018

Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

24 April 2018

Oct-1 POU and octamer DNA co-operate to recognise the Bob-1 transcription co-activator via induced folding

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

24 April 2018

Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

transcription coactivator activity

determination method or standard

1 reference

24 April 2018

Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

3 references

8 April 2019

Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

8 April 2019

Oct-1 POU and octamer DNA co-operate to recognise the Bob-1 transcription co-activator via induced folding

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

8 April 2019

Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

RNA polymerase II core promoter sequence-specific DNA binding

determination method or standard

1 reference

8 April 2019

Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

transcription coactivator activity

determination method or standard

2 references

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

RNA polymerase II transcription regulator complex

determination method or standard

2 references

biological process

regulation of transcription, DNA-templated

determination method or standard

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

humoral immune response

determination method or standard

1 reference

8 April 2019

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16633&geneProductId=UniProtKB:Q16633

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16633

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000376786

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000376786

ENSP00000433527

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433527

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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