Laminin subunit alpha 2 (Q21107899)

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mammalian protein found in Homo sapiens

merosin heavy chain
mutant laminin subunit alpha 2
laminin M chain
laminin, alpha 2
laminin-2 subunit alpha
laminin subunit alpha-2
LAMA2
laminin-12 subunit alpha
laminin-4 subunit alpha

Language	Label	Description	Also known as
English	Laminin subunit alpha 2	mammalian protein found in Homo sapiens	merosin heavy chain mutant laminin subunit alpha 2 laminin M chain laminin, alpha 2 laminin-2 subunit alpha laminin subunit alpha-2 LAMA2 laminin-12 subunit alpha laminin-4 subunit alpha

Statements

1 reference

13 November 2019

UniProt protein ID

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

Laminin G domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Laminin domain II, protein family

1 reference

based on heuristic

inferred from protein domain or family

Laminin alpha, domain I, protein family

1 reference

based on heuristic

inferred from protein domain or family

Laminin EGF domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Laminin IV domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Laminin, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

structural molecule activity

determination method or standard

1 reference

9 May 2019

Merosin, a tissue-specific basement membrane protein, is a laminin-like protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

signaling receptor binding

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

extracellular matrix structural constituent

determination method or standard

3 references

1 January 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24043&geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24043&geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24043&geneProductId=UniProtKB:P24043

determination method or standard

extracellular matrix structural constituent

determination method or standard

8 references

1 January 2018

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

1 January 2018

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

extracellular matrix structural constituent

determination method or standard

4 references

8 April 2019

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

extracellular matrix structural constituent

determination method or standard

5 references

9 May 2019

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

dendritic spine

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

basement membrane

determination method or standard

5 references

8 April 2019

Merosin, a tissue-specific basement membrane protein, is a laminin-like protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

8 April 2019

Laminin isoforms in fetal and adult human adrenal cortex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

extracellular matrix

determination method or standard

3 references

27 March 2018

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24043&geneProductId=UniProtKB:P24043

determination method or standard

27 March 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24043&geneProductId=UniProtKB:P24043

determination method or standard

27 March 2018

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24043&geneProductId=UniProtKB:P24043

determination method or standard

neuromuscular junction

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

collagen-containing extracellular matrix

determination method or standard

5 references

9 May 2019

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

basement membrane

determination method or standard

6 references

9 May 2019

Merosin, a tissue-specific basement membrane protein, is a laminin-like protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Laminin isoforms in fetal and adult human adrenal cortex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

biological process

muscle organ development

determination method or standard

1 reference

9 May 2019

Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

regulation of cell migration

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

positive regulation of synaptic transmission, cholinergic

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

regulation of embryonic development

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

regulation of cell adhesion

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

Schwann cell differentiation

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

extracellular matrix organization

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

animal organ morphogenesis

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

tissue development

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24043

determination method or standard

physically interacts with

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2095222

Laminin domain II

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

Laminin G domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

Laminin, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

Laminin alpha, domain I

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

Laminin EGF domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24043

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000400365

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400365

ENSP00000480802

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000480802

ENSP00000481744

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000481744

ENSP00000493888

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000493888

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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