Defensin alpha 3 (Q21107111)

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mammalian protein found in Homo sapiens

HP-3
defensin, alpha 3, neutrophil-specific
Defensin, alpha 3
neutrophil defensin 3
HP3
neutrophil peptide 3
HNP-3
DEFA3
defensin 3, neutrophil-specific

Language	Label	Description	Also known as
English	Defensin alpha 3	mammalian protein found in Homo sapiens	HP-3 defensin, alpha 3, neutrophil-specific Defensin, alpha 3 neutrophil defensin 3 HP3 neutrophil peptide 3 HNP-3 DEFA3 defensin 3, neutrophil-specific

Statements

1 reference

13 November 2019

UniProt protein ID

Alpha-defensin propeptide

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P59666

Beta/alpha defensin, protein family

1 reference

based on heuristic

inferred from protein domain or family

Defensin propeptide family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein homodimerization activity

determination method or standard

1 reference

8 April 2019

Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

molecular function

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

extracellular region

determination method or standard

extracellular exosome

determination method or standard

1 reference

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59666&geneProductId=UniProtKB:P59666

determination method or standard

azurophil granule lumen

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

extracellular space

determination method or standard

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59666&geneProductId=UniProtKB:P59666

determination method or standard

26 September 2017

Antimicrobial peptides in the first line defence of human colon mucosa

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59666&geneProductId=UniProtKB:P59666

determination method or standard

26 September 2017

Alpha-defensins 1-3 release by dendritic cells is reduced by estrogen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59666&geneProductId=UniProtKB:P59666

determination method or standard

26 September 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59666&geneProductId=UniProtKB:P59666

determination method or standard

extracellular space

determination method or standard

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

8 April 2019

Antimicrobial peptides in the first line defence of human colon mucosa

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

8 April 2019

Alpha-defensins 1-3 release by dendritic cells is reduced by estrogen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

8 April 2019

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

extracellular exosome

determination method or standard

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

biological process

defense response to fungus

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

intracellular estrogen receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Alpha-defensins 1-3 release by dendritic cells is reduced by estrogen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

defense response to bacterium

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

innate immune response in mucosa

determination method or standard

1 reference

26 September 2017

Antimicrobial peptides in the first line defence of human colon mucosa

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59666&geneProductId=UniProtKB:P59666

determination method or standard

defense response to virus

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

antimicrobial humoral response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method or standard

killing of cells of other organism

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

antibacterial humoral response

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

defense response to Gram-negative bacterium

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

defense response to Gram-positive bacterium

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

membrane disruption in other organism

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method or standard

3 references

8 April 2019

Antimicrobial peptides in the first line defence of human colon mucosa

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

8 April 2019

Antibacterial activity and specificity of the six human {alpha}-defensins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

cellular response to lipopolysaccharide

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59666

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P59666

Defensin propeptide

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P59666

Beta/alpha defensin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P59666

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000328359

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000328359

ENSP00000496106

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496106

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

UniProt protein ID

21 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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