Nuclear receptor co-repressor 2 (Q14914612)

SANT/Myb domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

N-CoR, GPS2-interacting domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SANT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

14 February 2019

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

sequence-specific DNA binding

1 reference

24 April 2018

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

transcription corepressor activity

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

protein N-terminus binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

transcription factor binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

1 reference

24 April 2018

histone deacetylase binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

Notch binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

protein binding

10 references

14 February 2019

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Mouse germline restriction of Oct4 expression by germ cell nuclear factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

chromatin binding

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

glucocorticoid receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

retinoic acid receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

protein-containing complex binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

retinoid X receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

chromatin binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

transcription corepressor activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

nuclear receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

histone deacetylase complex

cell component

1 reference

24 April 2018

The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

transcription repressor complex

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

chromatin

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

histone deacetylase complex

nucleus

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

positive regulation of protein deacetylation

biological process

1 reference

14 February 2019

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of fat cell differentiation

1 reference

14 February 2019

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

1 reference

24 April 2018

glucose homeostasis

1 reference

14 February 2019

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

in utero embryonic development

1 reference

14 February 2019

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of transcription by RNA polymerase II

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

24 April 2018

Unique forms of human and mouse nuclear receptor corepressor SMRT

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU42&geneProductId=UniProtKB:Q9WU42

1 reference

24 April 2018

telencephalon development

1 reference

14 February 2019

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

type I pneumocyte differentiation

white fat cell differentiation

1 reference

14 February 2019

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

forebrain development

1 reference

14 February 2019

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of transcription, DNA-templated

cell proliferation in forebrain

2 references

1 reference

14 February 2019

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of production of miRNAs involved in gene silencing by miRNA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of transcription by RNA polymerase II

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Cooperative regulation in development by SMRT and FOXP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Unique forms of human and mouse nuclear receptor corepressor SMRT

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

14 February 2019

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

negative regulation of androgen receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU42

1 reference

SANT domain

1 reference

N-CoR, GPS2-interacting domain

1 reference