Transcription factor 7 like 2, T cell specific, HMG box (Q14913903)

High mobility group box domain superfamily

1 reference

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CTNNB1 binding, N-teminal, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

1 reference

14 February 2019

transcription factor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

protein binding

5 references

14 February 2019

Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Bioinformatics and cellular signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

chromatin binding

Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse

2 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

gamma-catenin binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

armadillo repeat domain binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

beta-catenin binding

6 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

16 July 2018

TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

chromatin binding

Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

beta-catenin binding

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

14 February 2019

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

cell component

cytosol

1 reference

14 February 2019

T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

protein-DNA complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

beta-catenin-TCF7L2 complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

PML body

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

1 reference

14 February 2019

transcription regulator complex

1 reference

16 July 2018

T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

catenin-TCF7L2 complex

1 reference

14 February 2019

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

nucleoplasm

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

nucleus

9 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

10 September 2018

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

10 September 2018

T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

transcription regulator complex

nucleus

10 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of DNA-binding transcription factor activity

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

1 reference

16 July 2018

oligodendrocyte development

1 reference

14 February 2019

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

cellular response to starvation

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

secretory granule localization

1 reference

14 February 2019

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

cellular glucose homeostasis

1 reference

14 February 2019

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of protein kinase B signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

blood vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of hormone metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of myelination

1 reference

14 February 2019

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

face morphogenesis

1 reference

14 February 2019

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

embryonic digestive tract morphogenesis

1 reference

14 February 2019

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

glycogen metabolic process

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of epithelial cell proliferation

1 reference

14 January 2019

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

regulation of oligodendrocyte differentiation

1 reference

14 February 2019

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of gluconeogenesis

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of fat cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of fibroblast growth factor receptor signaling pathway

1 reference

14 February 2019

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of apoptotic process

1 reference

14 February 2019

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

glucose metabolic process

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

neural tube development

1 reference

14 February 2019

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

embryonic genitalia morphogenesis

1 reference

14 February 2019

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

embryonic hindgut morphogenesis

1 reference

14 February 2019

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of transcription, DNA-templated

odontogenesis of dentin-containing tooth

1 reference

14 February 2019

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of heparan sulfate proteoglycan biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of protein export from nucleus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of triglyceride biosynthetic process

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

insulin metabolic process

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of organ growth

1 reference

14 February 2019

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

fat cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

multicellular organism growth

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of skeletal muscle tissue development

1 reference

14 February 2019

Connective tissue fibroblasts and Tcf4 regulate myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of canonical Wnt signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

cell population proliferation

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

positive regulation of protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

post-embryonic development

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

skin development

1 reference

14 February 2019

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

pituitary gland development

1 reference

14 February 2019

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

bone mineralization

1 reference

14 February 2019

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of lipid biosynthetic process

1 reference

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

response to glucose

1 reference

14 February 2019

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

maintenance of DNA repeat elements

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

negative regulation of BMP signaling pathway

1 reference

14 February 2019

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of transcription by RNA polymerase II

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

somatic stem cell population maintenance

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

Wnt signaling pathway

Wnt signaling mediates regional specification in the vertebrate face

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

27 March 2018

27 March 2018

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

positive regulation of transcription by RNA polymerase II

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

The basement membrane of hair follicle stem cells is a muscle cell niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

14 February 2019

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

canonical Wnt signaling pathway

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

16 July 2018

16 July 2018

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q924A0&geneProductId=UniProtKB:Q924A0

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

canonical Wnt signaling pathway

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

14 February 2019

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

positive regulation of insulin secretion

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

glucose homeostasis

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

myoblast fate commitment

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q924A0

CTNNB1 binding, N-teminal

has part(s)

1 reference

High mobility group box domain

1 reference