Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (Q14912988)

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mammalian protein found in Mus musculus

Hadhb
TP-beta
trifunctional enzyme subunit beta, mitochondrial
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit

Language	Label	Description	Also known as
English	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta	mammalian protein found in Mus musculus	Hadhb TP-beta trifunctional enzyme subunit beta, mitochondrial hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Thiolase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thiolase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thiolase, acyl-enzyme intermediate active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thiolase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thiolase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transferase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

acyltransferase activity, transferring groups other than amino-acyl groups

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

catalytic activity

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

acyltransferase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

long-chain-3-hydroxyacyl-CoA dehydrogenase activity

determination method or standard

1 reference

31 January 2018

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

acetyl-CoA C-acyltransferase activity

determination method or standard

3 references

31 January 2018

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

Carnitine content and expression of mitochondrial beta-oxidation enzymes in placentas of wild-type (OCTN2( / )) and OCTN2 Null (OCTN2(-/-)) Mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

fatty-acyl-CoA binding

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

3-hydroxyacyl-CoA dehydrogenase activity

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

acetyl-CoA C-acyltransferase activity

determination method or standard

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Carnitine content and expression of mitochondrial beta-oxidation enzymes in placentas of wild-type (OCTN2( / )) and OCTN2 Null (OCTN2(-/-)) Mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

long-chain-3-hydroxyacyl-CoA dehydrogenase activity

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

protein-containing complex binding

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

mitochondrial outer membrane

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

endoplasmic reticulum

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

mitochondrial inner membrane

determination method or standard

4 references

31 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

Proteomic analysis of the mouse liver mitochondrial inner membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

mitochondrial fatty acid beta-oxidation multienzyme complex

determination method or standard

1 reference

31 January 2018

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

determination method or standard

7 references

31 January 2018

Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

31 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

determination method or standard

8 references

14 February 2019

Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

mitochondrial inner membrane

determination method or standard

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Proteomic analysis of the mouse liver mitochondrial inner membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

biological process

lipid metabolism

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

fatty acid metabolic process

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

determination method or standard

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99JY0&geneProductId=UniProtKB:Q99JY0

determination method or standard

fatty acid beta-oxidation

determination method or standard

4 references

14 February 2019

Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JY0

determination method or standard

Thiolase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

Thiolase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

Thiolase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

Thiolase, acyl-enzyme intermediate active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

Thiolase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99JY0

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000026841

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000026841

ENSMUSP00000110431

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000110431

ENSMUSP00000110434

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000110434

ENSMUSP00000118296

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118296

ENSMUSP00000142868

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142868

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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