MutS homolog 6 (Q14911719)

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mammalian protein found in Mus musculus
  • Msh6
  • mutS protein homolog 6
  • g/T mismatch-binding protein
  • p160
  • GTBP
  • mutS-alpha 160 kDa subunit
  • DNA mismatch repair protein Msh6
  • GTMBP
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Language Label Description Also known as
English
MutS homolog 6
mammalian protein found in Mus musculus
  • Msh6
  • mutS protein homolog 6
  • g/T mismatch-binding protein
  • p160
  • GTBP
  • mutS-alpha 160 kDa subunit
  • DNA mismatch repair protein Msh6
  • GTMBP

Statements

molecular function
cell component
biological process
DNA mismatch repair
determination method or standard
IGI
IEA
IMP
ISO
10 references
retrieved
27 March 2018
stated in
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
ISO
retrieved
27 March 2018
stated in
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
27 March 2018
stated in
Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
27 March 2018
stated in
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
27 March 2018
stated in
Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
27 March 2018
stated in
Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
27 March 2018
stated in
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IGI
retrieved
27 March 2018
stated in
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IGI
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IEA
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276
determination method or standard
IEA
DNA mismatch repair
determination method or standard
IBA
IEA
IGI
IMP
ISO
11 references
retrieved
9 May 2019
stated in
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
ISO
retrieved
9 May 2019
stated in
Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IGI
retrieved
9 May 2019
stated in
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IGI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IBA
somatic hypermutation of immunoglobulin genes
determination method or standard
IBA
IMP
5 references
retrieved
9 May 2019
stated in
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276
determination method or standard
IBA

Identifiers

 
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