Circadian locomotor output cycles kaput (Q14908776)

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mammalian protein found in Mus musculus
  • uniprot:O08785
  • circadian locomoter output cycles protein kaput
  • Clock
edit
Language Label Description Also known as
English
Circadian locomotor output cycles kaput
mammalian protein found in Mus musculus
  • uniprot:O08785
  • circadian locomoter output cycles protein kaput
  • Clock

Statements

molecular function
E-box binding
determination method or standard
IDA
IEA
ISO
6 references
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
ISO
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
CLOCK regulates circadian rhythms of hepatic glycogen synthesis through transcriptional activation of Gys2
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
core promoter sequence-specific DNA binding
determination method or standard
IDA
6 references
retrieved
24 April 2018
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
24 April 2018
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
24 April 2018
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
24 April 2018
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
24 April 2018
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
24 April 2018
stated in
p53 regulates Period2 expression and the circadian clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
protein binding
determination method or standard
IPI
37 references
retrieved
7 November 2018
stated in
CIPC is a mammalian circadian clock protein without invertebrate homologues
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
The polycomb group protein EZH2 is required for mammalian circadian clock function
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
A molecular mechanism for circadian clock negative feedback
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Core circadian protein CLOCK is a positive regulator of NF-κB-mediated transcription
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
A role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na retention
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Biochemical analysis of the canonical model for the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Rapid activation of CLOCK by Ca2 -dependent protein kinase C mediates resetting of the mammalian circadian clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Imaging of heme/hemeproteins in nucleus of the living cells expressing heme-binding nuclear receptors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
The NAD -dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Machine learning helps identify CHRONO as a circadian clock component
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
JNK regulates the photic response of the mammalian circadian clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
CLOCK-mediated acetylation of BMAL1 controls circadian function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Identification of two amino acids in the C-terminal domain of mouse CRY2 essential for PER2 interaction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
retrieved
7 November 2018
stated in
The BMAL1 C terminus regulates the circadian transcription feedback loop.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IPI
RNA polymerase II cis-regulatory region sequence-specific DNA binding
determination method or standard
IDA
8 references
retrieved
7 November 2018
stated in
p53 regulates Period2 expression and the circadian clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
The RelB subunit of NFκB acts as a negative regulator of circadian gene expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
cell component
cytoplasm
determination method or standard
IDA
IEA
5 references
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
nucleus
determination method or standard
IDA
IEA
ISO
8 references
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
ISO
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
CIPC is a mammalian circadian clock protein without invertebrate homologues
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
biological process
circadian regulation of gene expression
determination method or standard
IEA
IMP
ISO
11 references
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
ISO
retrieved
7 November 2018
stated in
CLOCK regulates circadian rhythms of hepatic glycogen synthesis through transcriptional activation of Gys2
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
positive regulation of transcription, DNA-templated
determination method or standard
IDA
IEA
IMP
ISO
11 references
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
ISO
retrieved
7 November 2018
stated in
CLOCK regulates circadian rhythms of hepatic glycogen synthesis through transcriptional activation of Gys2
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IMP
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Metastasis-associated protein 1 is an integral component of the circadian molecular machinery
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Dec1 and Dec2 are regulators of the mammalian molecular clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Circadian clock feedback cycle through NAMPT-mediated NAD biosynthesis
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
O08785
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IGI
IEA
ISO
7 references
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
ISO
retrieved
7 November 2018
stated in
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IGI
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IEA
retrieved
7 November 2018
stated in
A role for Id2 in regulating photic entrainment of the mammalian circadian system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA
retrieved
7 November 2018
stated in
DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O08785&geneProductId=UniProtKB:O08785
determination method or standard
IDA

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q14908776&oldid=2023073330"