Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α (Q102220441)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

title

Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

Jacquelyn Maher

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

author name string

Caroline C Duwaerts

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

Kevin Siao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

Russell K Soon

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

Chris Her

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

Takao Iwawaki

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

Aras N Mattis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

22 November 2020

publication date

20 November 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

22 November 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33219328 AND SRC:MED&resulttype=core&format=json

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

22 November 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Plasma cell differentiation requires the transcription factor XBP-1

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Endoplasmic reticulum stress plays a central role in development of leptin resistance

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Regulation of hepatic lipogenesis by the transcription factor XBP1

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Hepatic Xbp1 Gene Deletion Promotes Endoplasmic Reticulum Stress-induced Liver Injury and Apoptosis

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

X-box Binding Protein 1 Regulates Unfolded Protein, Acute-Phase, and DNA Damage Responses During Regeneration of Mouse Liver

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

ER stress signaling by regulated splicing: IRE1/HAC1/XBP1

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Integrated stress response of vertebrates is regulated by four eIF2α kinases

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Getting RIDD of RNA: IRE1 in cell fate regulation

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

XBP1s Is an Anti-lipogenic Protein

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE1α signaling

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

IRE1A Stimulates Hepatocyte-derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

The contribution of endoplasmic reticulum stress to liver diseases

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021

Endoplasmic reticulum stress in liver disease

1 reference

https://api.crossref.org/works/10.1038/S41418-020-00671-1

7 January 2021