Usually means: Operating system for DEC computers.
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We found 5 dictionaries that define the word TWENEX:

General dictionaries General (2 matching dictionaries)
  1. TWENEX: Wiktionary
  2. TWENEX: Dictionary.com

Computing dictionaries Computing (2 matching dictionaries)
  1. TWENEX: Free On-line Dictionary of Computing
  2. TWENEX: Encyclopedia

Medicine dictionaries Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Definitions from Wiktionary (TWENEX)

noun:  (computing, informal) The TOPS-20 operating system for the PDP-10 mainframe computer.

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