CCR is the basic and clinical intramural research program of the National Cancer Institute at the National Institutes of Health working to make breakthrough scientific discoveries to find cures and treatments for cancer. Our scientists work on a wide spectrum of biological and biomedical problems that range from visualizing and understanding the structure of individual genes and proteins and developing novel methods for drug discovery to inventing biomedical devices and technology and creating innovative ways to treat patients on clinical trials that take place in the NIH Clinical Center in Bethesda, Maryland. During the past two decades, work in CCR has led to numerous landmark scientific discoveries and made a positive public health impact, including the development of groundbreaking immunotherapy approaches, HIV/AIDS testing, the creation of a HPV vaccine and more. Our Principal Investigators lead teams of laboratory scientists, trainees, clinicians, patient-care providers and administrators to unlock scientific knowledge to advance the fight against cancer and HIV/AIDS. We are dedicated to reaching our vision of a fully inclusive workplace in CCR. At CCR, we do cancer research that benefits all. More information on career opportunities: https://ccr.cancer.gov/careers NCI Privacy Policy: https://www.cancer.gov/policies/privacy-security Engagement ≠ endorsement.
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📣 REGISTER NOW: Join us at our Scientific Symposium Celebrating Steven A. Rosenberg's 50 Years at National Cancer Institute (NCI) - September 26-27, 2024! Virtual attendance is also available via the registration link in the event description. 👇
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🎥 ONGOING AND RECRUITING CLINICAL TRIAL: "Immune Checkpoint Inhibitor Nivolumab for Patients with Rare CNS Cancers." More than 130 primary tumors of the central nervous system (CNS) have been identified. Most affect less than 1,000 people in the United States each year. Because these tumors are so rare, there are few proven therapies. This trial tests the use of Nivolumab—an immunotherapy drug—which triggers the immune system to recognize tumor cells and fight against tumor growth. Watch below to learn more. To request a consultation, your primary doctor should call 240-760-6010. 🧠 National Cancer Institute (NCI), NIH Clinical Center (CC), National Institutes of Health (NIH): Intramural Research Program (IRP) #CancerResearch #ClinicalTrial #PatientRecruitment #Innovation #Medicine
🗞 IN THE NEWS: Steven A. Rosenberg, M.D., Ph.D., Chief of the Surgery Branch, spoke with Healio about a novel cellular immunotherapy that shrank tumors among some patients with metastatic colon cancer. This discovery could pave the way for immunotherapy success with other solid, epithelial cancers. National Cancer Institute (NCI), National Institutes of Health (NIH): Intramural Research Program (IRP) #CancerResearch #Immunotherapy #ColorectalCancer #Innovation #Technology
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After being diagnosed with a rare brain tumor, Mikaeel discusses how returning to his job kept him focused and optimistic throughout treatment for his oligodendroglioma. http://spr.ly/6041Ya3Hc
📣 CANCER CURRENTS: In this Q&A, Stephanie Goff, M.D., Senior Research Physician in our Surgery Branch, talks about what’s known about CAR T-cell therapy and second cancers and what this issue means in general for patients and this area of research. Dr. Goff specializes in developing and testing gene-engineered T-cell therapies, including CARs. ➡ Read more: https://lnkd.in/dtaJXik6 National Cancer Institute (NCI), National Institutes of Health (NIH): Intramural Research Program (IRP) #CancerResearch #Immunotherapy #Innovation #Technology #Medicine
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Check out this interactive infographic with information about each of our funding opportunities for cancer training. Download here: https://lnkd.in/daH2G4FG
NATIONAL IMMUNIZATION AWARENESS MONTH: Cervical cancer kills 300,000 people globally each year, but it doesn’t have to be this way. With the human papillomavirus (HPV) vaccine and an increased emphasis on improving accessibility to screening methods like self-sampling, it is now possible to prevent cervical cancer entirely or catch it early enough to cure it. ➡ Learn more about the National Cancer Institute (NCI) Center for Cancer Research's role in the development of the HPV vaccine: https://lnkd.in/e8BnvrUc NCI Center for Global Health, National Institutes of Health (NIH): Intramural Research Program (IRP) #CancerResearch #CancerPrevention #Innovation #Vaccine #Medicine
UPCOMING EVENT: This engaging conversation will be held on August 19 and you won't want to miss it. Learn more. 👇 National Cancer Institute (NCI), NIH Office of Equity, Diversity, and Inclusion, National Institutes of Health (NIH): Intramural Research Program (IRP)
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NCI Center for Cancer Research reposted this
Lorlatinib (Lorbrena) is superior to crizotinib (Xalkori) as an initial treatment for people with ALK-positive advanced non-small cell lung cancer, according to new clinical trial results. Treatment with lorlatinib also helped to prevent new brain metastases. https://go.nih.gov/QqWbno9 Image Credit: Gaillard F, Cerebral - Radiopaedia https://lnkd.in/edTnhhHS CC BY-NC-SA 3.0
💡 NEW FINDINGS: CCR researchers recently revealed new insights into calcineurin’s role in T-cell receptor (TCR) signaling. Calcineurin is a protein phosphatase that plays many important roles in the body. This finding was led by Jonathan D. Ashwell, M.D., who recently became an NIH Scientist Emeritus in the Laboratory of Cellular and Molecular Biology. Before his retirement, his lab worked to understand the physiologic and pathologic regulation of signaling in T cells. ➡ Read more: https://lnkd.in/ewqZ6CFJ National Cancer Institute (NCI), National Institutes of Health (NIH): Intramural Research Program (IRP) #CancerResearch #CancerBiology #Innovation #Health #Medicine