Latest stories from the Sanger Institute June 2024

Immune response study explains why some people don't get COVID-19

Scientists have discovered novel immune responses that help explain how some individuals avoid getting COVID-19. Using single-cell sequencing, researchers from the Wellcome Sanger Institute and their collaborators studied immune responses against SARS-CoV-2 infection in healthy adult volunteers as part of the world’s first COVID-19 human challenge study. Not all exposed participants went on to develop an infection, allowing the team to uncover unique immune responses associated with resisting sustained viral infection and disease. Read more…

Targeted treatment of sepsis and profile on Emma Davenport

Sepsis patients could be treated based on their immune system’s response to infection, not their symptoms. New research from Emma Davenport’s team uncovers how different people respond to sepsis based on their genetic makeup, which could help identify who would benefit from certain treatments and lead to the development of targeted therapies. Read more…

Emma Davenport’s team aims to help develop more personalised treatments by combining functional genomics data with clinical information. Here, Emma explains how her career has evolved and shares her experience as a female faculty member at the Wellcome Sanger Institute. Read more…

Ancient DNA will offer clues for climate-resilient crops

In the face of climate change and its threats to biodiversity, researchers are turning to an unconventional source – ancient environmental DNA – to help develop more sustainable and climate-resilient crops for the future. A new pioneering research project will analyse DNA fragments preserved in soil, ice or water spanning thousands to millions of years. By understanding how the ancestors of modern crops such as wheat, barley, and rice genetically adapted to past climate shifts and environmental pressures, researchers aim to uncover strategies for breeding crops capable of withstanding escalating climate impacts. Read more...

Mapping malaria genomes in West Africa and beyond

Alfred Amambua-Ngwa is a Professor at the Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine (MRC Unit The Gambia at LSHTM) and one of five current Sanger Institute International Fellows. He is dedicated to understanding and combatting malaria using genomics. In this interview, Alfred shares his journey over the last two decades, highlighting key milestones and ongoing efforts driving the fight against malaria in Africa. Read more...

The secret lives of nematodes

C. elegans, a workhorse of modern biology, was the first multicellular organism to have its DNA code sequenced in 1998. But it is just one of potentially millions of nematode species. We explore the latest work to sequence the genomes of hundreds of nematodes and put C. elegans in its evolutionary context. Read more...

Careers at Sanger Institute

Meet our people

Life at the Sanger Institute is truly unique where collaboration, innovation and support for people as individuals are demonstrated in everything we do. Set across 130 acres, just outside of Cambridge, our people are shaping the future by delivering life-changing science with the reach, scale, and creativity to solve some of humanity’s greatest challenges.

We have over 1,200 people at the Sanger Institute, from 70 nationalities. Explore what our employees, students, and alumni from across our Institute have to say about what they do, life at Sanger Institute and more.

Current jobs

Scientific Manager: A rare opportunity has arisen for a talented Scientific Manager to join the Cellular Operations team here at the Wellcome Sanger Institute. CellOps is composed of multiple teams specialising in cell biology-based fields.

Sequencing Operations, Sample Preparation- Team Lead: The team has expanded its extraction portfolio and is looking for a highly proficient manager to coordinate the rapidly changing workloads and expectations of numerous projects in parallel while delivering high-quality data.

See all our jobs

Copyright (C) 2024 Wellcome Sanger Institute. All rights reserved.

For more stories from the Wellcome Sanger Institute visit: http://sangerinstitute.blog/