Bruker BioSpin Newsletter #12

New TopSpin 4.4 Release!

We have focused on enhancing NMR workflows with Artificial Intelligence in the latest TopSpin 4.4 software release, incorporating AI-based data processing and analysis methods. The fully automated deconvolution represents a significant advancement in data processing and analysis automation. Additionally, TopSpin 4.4 includes enhanced usability features, such as the pulse program editor in combination with a graphical display and updated command-line help.

Download it now: https://goto.bruker.com/3QyRlVe

Celebrating One Year of Growth and Innovation at the Bruker Store

The Bruker Store was relaunched in April 2023 and we are proud to announce that it has been a successful year of growth and innovation! Discover the top 5 key highlights tailored to provide you with the best possible experience.

Visit https://goto.bruker.com/3yaMtQ0

Research Using NMR* Uncovers New Biomarkers of Metabolic Syndrome

Metabolic syndrome (MetS) is a clustering of five conditions that includes abdominal obesity, diabetes, and high blood pressure. One quarter of the developed world population is estimated to have the condition (1). It is associated with the risk of coronary heart disease, stroke, and other conditions that affect the blood vessels (2). Diagnosis of MetS can be challenging as there is a lack of consensus about a definition of the condition. It is often associated with lifestyle factors such as poor diet and physical inactivity, but there are also genetic factors that put some people at higher risk.

Read the article: https://goto.bruker.com/3UwVTgg

*Research use only. Bruker NMR instruments are not intended for use in clinical diagnostic procedures.

New EPR and NMR EduLabs

Join #Educate2Resonate, the online community platform for NMR and EPR enthusiasts, and explore our new EduLabs! Discover the EPR guide to beer freshness, the mysteries of dark chocolate, and the brewing process with "Brewing Alcohol 1:1". Start experimenting today!

Download EduLabs: https://goto.bruker.com/3Uw2yr4

Regulatory Guidance on NMR for Biologics, Peptides and Oligos

In 2023 we’ve seen the approval of weight loss drugs, which has had an impact not only on the population suffering from obesity but also on society at large and the industry itself.

1. Development of Therapeutic Protein Biosimilars: Comparative Analytical Assessment and Other Quality-Related Considerations. Guidance for Industry.

2. Guideline on the Development and Manufacture of Synthetic Peptides

3. ANDAs for Certain Highly Purified Synthetic Peptide Drug Products That Refer to Listed Drugs of rDNA Origin Guidance for Industry

4. Draft Guidance on Givosiran Sodium

Advancing Battery Manufacturing with Magnetic Resonance

Listen to Oliver Pecher Ph.D., CEO of ePROBE, in this highly informative series of interviews and learn about In-situ NMR showing great potential to become a standard approach for routine monitoring of electrochemical processes under operating conditions.

Watch all the interviews: https://goto.bruker.com/3QAh0gs

On-Demand Webinar

Streamlined Juice Analysis With the Powerful New Update of the NMR Juice-Profiling Method

Fruit juice analysis is time-consuming and requires the implementation of various analytical instruments and numerous analytical methods. The NMR Juice-Profiling method helps to save considerable time and cost for traditional analyses, while simultaneously providing additional information such as geographical origin, thanks to the statistical analysis of the NMR profiles.

Watch now: https://goto.bruker.com/4bULpz1

Spectral Instruments Imaging UnveilsAura 4.5 with New Kinetics Feature

We are excited to announce that Spectral Instruments Imaging, the performance leader in preclinical optical imaging solutions, has launched Aura 4.5, the latest version of their in vivo imaging software. 

This feature release introduces the highly anticipated Kinetics mode, a revolutionary, new way for researchers to capture and analyze dynamic bioluminescent signals automatically, in real-time.

 “Kinetics is one of those rare features that both makes your life easier and improves the quality of your data – it’s a real game-changer!” Bo Nelson, Chief Technology Officer at Spectral Instruments Imaging, emphasizes “Our continuous improvement of Aura Software is driven by the mission to ensure you can capture and analyze data quickly, easily and accurately. It’s important to us that all users be able to take full advantage of the unrivaled sensitivity of the Lago X, Ami HTX and Kino in vivo imaging systems – without being intimidated or feeling like they need to be experts.”

Read more: https://goto.bruker.com/4btBijw