Transgene’s Post

' Cold is gold ' - Cryobiopsy - Lung cancer ! 75 year, female, no comorbidities Complaints: Cough , loss of appetite and weight - 3 months CT Chest : Mass lesion in right upper lobe Referred for Bronchoscopic biopsy of mass lesion Procedure : Rigid bronchoscopy Radial EBUS Cryolung biopsy (1.1 mm cryoprobe) Fogarty balloon occlusion Imprint cytology: Atypical cells suggestive of malignancy Cryobiopsy - Histopathology- Adenocarcinoma lung No procedural complications 1.1 mm cryoprobe : Advantages - helps in reaching distal lung segments - biopsy - smaller nodules ( Both concentric and eccentric lesions on Radial EBUS ) - Less bleeding incomparison to larger probes Department of Interventional Pulmonology Yashoda Hospitals , Somajiguda, Hyderabad Amol Patil Pranshu Abhishek Erbe Group FUJIFILM India Pvt Ltd Balu Mahendran Dheeraj Chaudhri

Liquid is Solid.

The findings of this study showed that serial testing using Guardant Health’s blood-based minimal residual disease test increases sensitivity for detecting recurrence in patients with Stage II & III Colon Cancer.¹ Serial testing measurements increase sensitivity up to 80% versus a single test measurement at Day 28 post-surgery.¹ The ability of Guardant Health’s comprehensive liquid biopsy to detect minimal residual disease is one of many factors that makes our liquid biopsy solid. Speak to your doctor today about minimal residual disease (MRD) testing with a simple blood draw. Visit us at https://lnkd.in/gHNdYtQN to find out more about our MRD test which can help oncologists identify patients at a higher risk of recurrence. Reference: 1. Yoshiaki Nakamura et al. Multiomic Analysis for Minimal Residual Disease Detection: Addressing Challenges in Stage II-III Colon Cancer from COSMOS CRC-01. ASCO GI. 2024. #guardanthealth #guardanthealthamea #liquidbiopsy #liquidissolid #MRD #minimalresidualdisease #colorectalcancer #CRC #comprehensivegenomicprofiling #nextgenerationsequencing #NGS #cancerpatients #medicaloncologists

https://lnkd.in/gs4VZ6hh Article title: Tumor lysis syndrome after chemotherapy for metastatic colic carcinoma: About two adult cases   Author(s): Abaza H; Sallami S; Ben Chaabene A; Gara S   Journal: Archives of Clinical Gastroenterology   Journal ISSN: 2455-2283 Abstract: Tumor Lysis Syndrome (TLS) is a major oncological emergency involving metabolic perturbations. It occurs when tumor cells release their contents into the bloodstream, either spontaneously or in response to therapy. TLS is characterized by hyperuricemia, hyperkalemia, hyperphosphatemia and hypocalcemia following massive lysis of malignant cells. Although this syndrome is well described, it is rarely seen or suspected in solid malignancies. The frequency and severity of TLS is partly dependent upon the biology of the disease and type of therapy administered. We report in this work two cases of tumor lysis syndrome occurring after chemotherapy for endocrine colon carcinoma with small metastatic cells. #Cancer #LysisSyndrome #Chemotherapy #Colon #Hyperuricemia #InflammatoryBowelDisease #FunctionalGIDisorders #GastrointestinalAndLiverDisease #DigestiveOncology #GastrointestinalSurgery #PediatricGastroenterology #ColorectalCancer #PancreaticCancer #HepatocellularCarcinoma #GastrointestinalBleeding #Endoscopy #Peertechz #PeertechzPublications #SurgicalGastroenterology #StomachUlcers #VirtualColonoscopy #GastricUlceration #RouxenYGastricBypass #GastricAcidSecretion #GastricMucosa #GastricUlcerHealing #GastricCardiaCancer #ReproductiveEndocrinology #EndocrineDisorders #Hepatology #AlimentaryCanal #PancreasCancer

->30years old male presented with metastatic rhabdomyosarcoma with intra-abdominal tumor. ->CT-CHEST investigation was done in precontrast and contrast phase( arterial and venous phase). Discussion: Rhabdomyosarcoma is a malignant tumor that originates from the immature muscle cells call rhabdomyoblasts. * The clinical presentation varies depending on the location of a tumor. However, in general, rhabdomyosarcomas are rapidly growing masses. They cause localized pressure effects on neurovascular structures and have a predilection for infiltrating bones. Pathological fractures can therefore occur. * increased incidence of rhabdomyosarcomas is seen in patients with a variety of syndromes and congenital anomalies, including: neurofibromatosis type I (NF1) andmaternal use of cocaine and marijuana. * On CT scan,rhabdomyosarcoma, often presents with the following characteristics: 1)Mass Lesion: It usually appears as a well-defined or irregularly shaped mass. 2)Heterogeneous Enhancement: Due to areas of necrosis, bleeding, or differing degrees of cellularity, the tumor may exhibit heterogeneous enhancement following contrast injection. 3).Invasion of Surrounding Structures: The tumor has the potential to spread to nearby organs or tissues, including the kidney, liver, spleen, pharynx, and vascular systems. 4. Regional Lymphadenopathy 5. Calcifications. Additional histopathological study and clinical correlation are frequently required for a conclusive diagnosis. #CTradiographers #CTspecialist #CTeducation #cancercases #Computedtomography

What is a biopsy and why is it performed? What are the limitations of a biopsy? Learn more at MyPathologyReport.ca. #patienteducation #healthliteracy #medicine #patientcare #patientengagement #pathology #pathologyreport #askapathologist #biopsy #cancer #cancercare https://lnkd.in/eUsbAvKY

What a pleasure it is to share with you the results of our randomized trial comparing Endoscopic Submucosal Dissection and piece-meal EMR: https://lnkd.in/e2Q_ragT 10 years of work with my friends co-authors of the study to master the technique, develop new strategies, create a national training program and prove its place as a first-line treatment for large benign colon lesions. When it is mastered, ESD should not be considered as over-treatment of large benign lesions! #one shot treatment #cure covert cancer #no recurrence Mathieu Pioche Timothée Wallenhorst Jeremie Albouys Vincent Lepilliez Marion Schaefer CHU de Limoges Stanislas Chaussade Maximilien Barret SFED - Société Française d'Endoscopie Digestive Thomas Rösch Alessandro Repici Philippe Leclercq Zacharias P. Tsiamoulos Pradeep Bhandari Eduardo Albéniz Arbizu Paraskevas Gkolfakis, MD, PhD, FESGE, FEBGH Ludovico Alfarone Jens Aksel Nilsen Alexander Schlachterman Yen-I Chen, MD, MSc Michał Kamiński

The first RCT comparing ESD and EpMR for large colonic lesions.

What is a biopsy and why is it performed? What are the limitations of a biopsy? #patienteducation #healthliteracy #medicine #patientcare #patientengagement #pathology #pathologyreport #askapathologist #biopsy #cancer #cancercare https://lnkd.in/eGwjHEvF

 #lungcancerscreening program in Croatia, lends globally and socially relevant insights to early screening. Lung Cancer Policy Network announcement and Sebastian Schmidt's post 🔗 in comments Bottom Line: 🔍 Detection Rates Comparison: Detection for Stage I/II reached 47%, surpassing rates in countries without screening, such as Germany (23%). 💉 Treatment Focus: The majority of patients underwent surgery, indicating a significant portion with curative intent. 📊 Quality Indicators Clarification: A high rate of stage IV cancers in a screening program doesn't necessarily reflect on the screening program's quality. Instead, it serves as an indicator of the healthcare system and overall environment. 🌐 Future Initiatives: Ongoing efforts involve embracing improved diagnostics, such as Next-Generation Sequencing (NGS). These advancements specifically target late-stage cancers like Pancreatic, CRC, Lung, and Ovarian. 💡 Potential Impact: These diagnostic enhancements have the potential to revolutionize healthcare systems, not just clinically but also economically. Improved targeted therapy in earlier lines could redefine the significance of early screening, making it a valuable healthcare intervention. #healthcareinnovation #cancerscreening #earlydetectionmatters #precisiononcology #healthcareimpact