Seno Medical’s Post

【Diagnostic Dilemma of Intracardiac Mass: Tumor versus Thrombus-Case Series and Systematic Review】 Full article: https://lnkd.in/g8thXGKw (Authored by Indira Acharya, et al., from Medstar Health (USA), etc.)   The differential diagnosis for intracavitary #cardiac_masses is limited, typically including vegetations, tumors, or thrombi. And cardiac thrombi can often mimic cardiac tumors on imaging, creating a diagnostic challenge. This work discusses and illustrates challenging cases involving intracardiac masses, focusing on the diagnostic complexities between #cardiac_thrombi and tumors, along with their respective management considerations and implications. #Echocardiography #Arrhythmias

Perspectum's biomarker scientist, Charlie Diamond will present tomorrow at #EASD in Madrid on "Quantitative multi-organ imaging stratifies high risk individuals, with cardiac and abdominal phenotypes in individuals with diabetic retinopathy." Join us to explore how our multi-organ imaging suite advances the understanding of metabolic diseases. #Perspectum https://lnkd.in/eThAeHGk

No Ray of Sunshine Why routine chest x-rays? A quick check of reasonable estimates of sensitivity and specificity ( Samuel VJ, Gibikote S, Kirupakaran H. Ind J Radiol Imaging 2016; Parikh R, Mathai A, Parikh S, et al. Indian J Ophthalmol 2008) : sensitivity 0.5 approximately , specificity 0.996; not a bad screening test as a good screening test has sensitivity specificity = 1.5 or greater (Power M, Fell G, Wright M BMJ Evidence-Based Medicine 2012.) The risk of #cancer associated with a routine CXR is lower than the risk of death driving to the x-ray facility. A wonderful summary of risk and exposure was published a few years ago (Verdun FR, Bochud F, Gudinchet F, et al. RSNA 2008) with a nice follow-on a few years later ( Lin EC. Mayo CLin Proc 2010). An aside, a single #CXR is equivalent to 10 days of ambient radiation exposure. The cost of a chest x-ray is between $230 - $600 (US). (https://lnkd.in/gq3iA4M4) For ease, let us put the value at $400. CXR of 4113 persons resulted in 7 with clinically significant findings. Alternatively, 4113*400/7 = $411,300.00 for one significant finding. Side comment: In my patient population, I expect the cost is closer to $1,000,000 per finding. #xray #clinicalresearch #clinicaltrials #drugdevelopment

⚕ Head and Neck Soft Tissue Sarcoma Patient: Age and Tumor Region Are Predictive in Disease-Free Survival and Overall Survival, by #JOMS 🍀https://lnkd.in/eCNArtpp

Hi everyone Hope everyone is good health A very nice case has been diagnosed this morning. Although, everyone is aware of lung carcinoma but this one is different. A 26 year old was referred to us by pulmonologist because of presence of a well demarcated solid nodule of 4.1 cm in diameter that was enhanced on CT scan in the cardio phrenic angle . We suspected it to be a mediastinal nodule, such as thymoma. A systemic CT examination revealed no tumors other than this tumor. The lung was deflated to confirm the nodule. The histopathological findings revealed a well demarcated nodular lesion composed of proliferation of spindle cells, admixed with some pleomorphic cells arranged in a fascicular fashion with ropey collagen fibers associated with variably dilated blood vessels exhibiting staghorn like appearance, involving the pleural tissue and the pulmonary alveolar tissue. Mitotic figures were few and Immunohistochemically shows positive for CD34 , bcl-2 and STAT6, whereas alpha-SMA, desmin, and S-100 were negative. Based on above facts and as per recent WHO Classification Of Lung Tumors the diagnosis of fibrous tumor of the lung was given. karyotyping was done which revealed very unusual presentation revealing 48,X,−Y, 7, 12, 17 #karyotying #deflation #of #the #lungs #to #determine #acccurate #diagnosis #stapling #device #biopsy #chemoradiation #pleurodesis

Hi everyone Hope everyone is good health A very nice case has been diagnosed this morning. Although, everyone is aware of lung carcinoma but this one is different. A 30 year old was referred to us by pulmonologist because of presence of a well demarcated solid nodule of 3.6 cm in diameter that was enhanced on CT scan in the cardio phrenic angle . We suspected it to be a mediastinal nodule, such as thymoma. A systemic CT examination revealed no tumors other than this tumor. The lung was deflated to confirm the nodule. The histopathological findings revealed a well demarcated nodular lesion composed of proliferation of spindle cells, admixed with some pleomorphic cells arranged in a fascicular fashion with ropey collagen fibers associated with variably dilated blood vessels exhibiting staghorn like appearance, involving the pleural tissue and the pulmonary alveolar tissue. Mitotic figures were few and Immunohistochemically shows positive for CD34 , bcl-2 and STAT6, whereas alpha-SMA, desmin, and S-100 were negative. Based on above facts and as per recent WHO Classification Of Lung Tumors the diagnosis of fibrous tumor of the lung was given. karyotyping was done which revealed very unusual presentation revealing 31,XY,add(1)(q21), 4, 8, 9, 14, 18, 21, mar[cp6] #karyotying #deflation #of #the #lungs #to #determine #acccurate #diagnosis #stapling #device #biopsy #chemoradiation

The FDA Mandate on Breast Density Inform law goes into effect on 10th September. Which technologies could be offered to provide supplemental screening for women with #densebreasts? 👉 Invenia ABUS is the first FDA approved ultrasound supplemental screening technology for dense breasts 👉 Impactful evidence demonstrates additional cancer findings. ABUS picks up invasive cancers at an early and treatable stage. Those cancers would have been missed with mammography 👉 It's using latest #ultrasound technology from #GEHealthCare supported by #AI assistant to reduce reading time by 33% 👉 And most important: 100% of women would recommend the non-invasive ABUS to their best friend. Curious? Learn more here: https://lnkd.in/eJTVQGJg

#WeeklyPodcast Ana Luzarraga-Aznar discussed about the molecular profile as predictor of #EndometrialRecurrence 🎙️ https://bit.ly/3Wu88g7 🔆Highlights 🧬Molecular subgroups of #endometrialcancer present distinctive recurrence patterns: p53-abn tumors relapse mostly with peritoneal and distant disease, and NSMP tumors at distance 🧬Molecular profile is a stronger independent predictor for vaginal, peritoneal, and distant recurrence than classic histologic factors 🧬P53-abn is the sole independent predictor of peritoneal relapse 🧬P53-abn and NSMP are independent predictors of #distantrecurrence #LeadArticle #IJGConline #Research #Prevention #Treatment #Diagnostic #GynCancer #GynOnc #WomenHealth #SoMe #SoMe4GynOnc

Fine Needle Aspiration (FNA) cytology is a minimally invasive diagnostic technique utilized by healthcare professionals to examine tissue samples obtained from various body parts, such as thyroid nodules, breast masses, and lymph nodes. Developed in the 1970s, FNAC has emerged as one of the most valuable tools for diagnosing diseases accurately while reducing surgical interventions. This blog will discuss its background, importance, advantages, limitations, and applications across different medical fields. https://lnkd.in/g4Teu99S #BhaloTheko

https://lnkd.in/eWwKK--4                                                                               Article title: Primary pulmonary myxoid sarcoma: A case report and review of the literature   Author(s): Hollis Hutchings; Erik Schwarze; Beena Ahsan; Jessica Cox; Ikenna Okereke* Journal: Global Journal of Perioperative Medicine   Journal ISSN: 2641-3124 Abstract: Background: Primary pulmonary myxoid sarcoma is a very rare tumor, with less than 25 cases being described in the literature. When found in the bronchial tree, an R0 resection with post-operative follow-up is sufficient for curative treatment. We present a case of primary pulmonary myxoid sarcoma in a middle-aged man with an associated review of the literature to highlight this rare tumor. #PrimaryPulmonaryMyxoidSarcoma #LungCancer #LungResection #PreoperativeTesting #CardiovascularMedicine #PulmonaryCare #Peertechz #PeertechzPublications #Anticoagulation #MedicationManagement #SurgicalOutcome #EvidenceBasedCare #PreoperativeEvaluation #SurgicalRiskScoring #PerioperativeGuidelines #HaemodynamicMonitoring #SurgicalOptimisation #EnhancedRecoveryPrograms #CardiopulmonaryExerciseTesting #PerioperativeFluids