🧫 Studying infectious disease? Make 35 steps forward in your research with the latest addition of 35 lab-tested dPCR microbial assays to our portfolio. Use these new microbial targets, mostly for urinary tract infections, sexually transmitted infections, tropical and vector-borne diseases, to: - Improve accuracy and specificity, while reducing cross-reactivity - Find low-abundance targets - Monitor emerging or less common pathogens - Gain a better understanding of microbial dynamics and interactions Discover the assays. ✅ https://lnkd.in/e89EmyAu
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My first (first-author) paper is finally published in the latest issue of JBC! Our work highlights the different approaches that control the expression of genes required for Salmonella infection. Thank you to the other authors who contributed to this study! https://lnkd.in/gS4z-gHF
HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids
sciencedirect.com
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To enhance your understanding of the antiviral properties of octominin (a novel AMP derived from Octopus minor) against three potentially harmful fish viral strains, we encourage you to explore our most recent publication. https://lnkd.in/gSJQhqeE
In-vitro immunomodulatory responses and antiviral activities of antimicrobial peptide octominin against fish pathogenic viruses
sciencedirect.com
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Precision Calibration; Comprehensive Coverage of pathogen; Bridge from Research to Clinical use, #Hecin #PCRREFERENCE monitors the whole process of #PCRtest and makes reliable result! Visiting the offical website to find targeted products: hecin-scientific.com #RealtimePCR #HecinScientific #PCRqualitycontrol #ReadtousePCRmastermix
Accurate detection results are crucial for developing effective prevention and treatment strategies in virology research and diagnostics. Our PCR virus reference standards offer reliable support with the following features: Precision Calibration Comprehensive Coverage Bridge from Research to Clinical Applications Product List: No. Pathogen Name 1 Streptococcus canis 2 Streptococcus dysgalactiae 3 Streptococcus mitis 4 Streptococcus oralis 5 Streptococcus pyogenes 6 Syphilis spirochetes 7 Trichomonas vaginalis 8 Ureaplasma urealyticum 9 Vibrio campbellii 10 Vibrio cholerae 11 Vibrio parahaemolyticus 12 Vibrio vulnificus For more information or to request a complete product list, please contact us via email at [email protected] https://lnkd.in/gw66vcSZ #PCR #VirusReferenceStandards #VirusDetection #ClinicalDiagnostics #VirusResearch #HighAccuracy #HighStability #PublicHealth
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Discovery of the exact mechanism of Coronavirus cell entry. The two Coronaviruses MERS and SARS-COV-2 do enter human alveolar cells by exposing the S (B) subunit of their spike proteins, that bind ACE 2 on host cells and then fuse cell membrane and enter the cell. Her's a point, spike protein must exist in open state to expose its S (B) unit before attaching cell. Does this conformational change occurs spontaneously or requires a regulator? In this study researchers discovered that it is Sialoglycan that bind the spike protein of the virus before infection to prime the exposure of S(B), which bind ACE 2 and allow virus entry. #nature #covid19 #coronavirus #SARS_CoV_2 https://lnkd.in/dH7RZS6y
Sialoglycan binding triggers spike opening in a human coronavirus - Nature
nature.com
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The inflammasome is a key part of our innate immune system, providing protection against invading pathogens. It also plays a role in initiating the adaptive immune response by stimulating macrophages and regulating the differentiation of Th17 cells. The NLRP3 inflammasome, specifically, has been linked to metabolic disorders, allergic reactions to environmental stimuli, and is thought to contribute to the cytokine storm observed in COVID-19. #inflammasomepathway #inflammation #immunesystem
Inflammasome Pathway
antibodies-online.com
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The inflammasome is a key part of our innate immune system, providing protection against invading pathogens. It also plays a role in initiating the adaptive immune response by stimulating macrophages and regulating the differentiation of Th17 cells. The NLRP3 inflammasome, specifically, has been linked to metabolic disorders, allergic reactions to environmental stimuli, and is thought to contribute to the cytokine storm observed in COVID-19. #inflammasomepathway #inflammation #immunesystem
Inflammasome
antibodies-online.com
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Does your lab take a targeted approach to differentiating bacterial, viral, and parasitic GI infections? ALPCO offers real-time PCR/RT-PCR kits for molecular testing of gastrointestinal pathogens that provide rapid results in fewer than 1.5 hours. To learn more about the flexibility of our kits, visit: bit.ly/3sjRdQc #Molecular #MolecularTesting #PCRTesting #PCRKits #GIInfections
Real-time PCR/RT-PCR Products for Gastrointestinal Pathogen Detection
alpco.com
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PBMCs have been studied to help find better ways to diagnose, test for drugs, and create immune systems that are stronger against parasites like T. gondii (Acosta JA. and Hernandez A., 2019). Even though peripheral blood mononuclear cells (PBMCs) can not perfectly replicate an infection in living organisms, they can be taken directly from patients and produce certain traits that, when added to the guidelines, can make treatment better. Ref: Acosta JA. and Hernandez A., (2019). An Overview of Peripheral Blood Mononuclear Cells as a Model for Immunological Research of Toxoplasma gondii and Other Apicomplexan Parasites. Front. Cell. Infect. Microbiol: FCIM, 9(24), doi: 10.3389/fcimb.2019.00024
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