OEM by QIAGEN’s Post

A new mention of Abyntek Biopharma at iScience entitled “The Prc and CtpA proteases modulate cell-surface signalling activity and virulence in Pseudomonas aeruginosa”.   Scientists from CSIC have identified new proteases that regulate the activity of cell surface signaling systems. These systems are especially present in bacteria of the Pseudomonas genus, allowing them to adapt and survive in various environments. To achieve this result, they have used a custom-made #antibody made by Abyntek Biopharma against Fox-A.   👉 Check out the article: https://lnkd.in/dg_Juc3s   ⚗ Find out our custom services: https://lnkd.in/ecYBPUk5 #Antibodies #Bioreagents #Regents #Biotech

No matter the project size, we want to help you achieve your commercialization. Our custom services are here to build your assay components to the exact specifications you need! Download the handbook with tips and resources on streamlined commercialization! #assaydevelopment #biotech

#Article now available! #Proteincharacterization using variable pathlength #spectroscopy: high- & low-concentration methods In this article, Paul Mania (Bioanalytics Applications Specialist, Repligen Corporation) and Nigel Herbert (Senior Bioanalytics Applications Specialist, Repligen Corporation) describe the use of variable pathlength technology for #proteinconcentration measurement, with a particular focus on exploring low- and high- concentration methodologies Read this article to: • Learn how ultraviolet-based variable pathlength technology (VPT) avoids many of the pitfall of traditional fixed-pathlength ultraviolet-visible spectroscopy • Explore factors to ensure effective measurement of both high- and low-concentration samples using #VPT • Investigate data from #VPTcasestudies Read this article below:

#biologynotes One-step RT-PCR vs. Two-step RT-PCR. Generally, one-step RT-qPCR is best suited for applications requiring high-speed and high-throughput amplification of many samples with few targets, at the cost of potential efficiency and yield. Two-step RT-qPCR excels at allowing optimization, which provides greater sensitivity and flexibility, but reduces throughput. #molecularbiology #genesynthesis #biotech #reverseTranscription #RTPCR #PCR

Over the past 50 years, plasmid DNA has proven to be an indispensable biological tool with a wide variety of applications in biotech, academia, and clinical laboratories.   Discover everything you need to know about the fundamentals of plasmid DNA in our latest crash course! Learn more: https://lnkd.in/gZrY7vMK   ----- #Plasmid #DNA #Purification #LifeScience #Biotech #Biotechnology

🧬 Discover the latest innovation in dsRNA detection with our EasyAna dsRNA Quantitative Detection Kit (DD3509EN)! 🔬 No cross-reaction with other RNA types or interference from IVT reaction enzymes – just accurate results every time. See the data chart above for confirmation! 🔗 Follow the article to learn more >>https://bit.ly/3Pi7cXP #biotech #lifescience #dsRNA #mRNA #EasyAna

[Join us live] 🗓️ Join us on March 19th at the Bioprocessing summit Europe, where Rok Žigon will discuss the optimization of AAV downstream process development from harvest to final product. ℹ️ This presentation will cover considerations and examples of case studies for various AAV serotypes for all DSP steps. Join us to learn about: ✔️data from initial lysate clarification and pre-capture options to reduce contaminants, ✔️comparison of affinity and ion-exchange capture step ✔️optimization of polishing (full enrichment) step on various monolithic columns, all supported with orthogonal analytics.  ✏️ Register here: https://lnkd.in/dCWrgbdi #AAV #downstream #DSP #biotech #purification

𝗜𝗱𝗲𝗮𝘆𝗮 𝘀𝗵𝗼𝘄𝗰𝗮𝘀𝗲𝘀 𝗽𝗿𝗼𝗼𝗳-𝗼𝗳-𝗰𝗼𝗻𝗰𝗲𝗽𝘁 𝗱𝗮𝘁𝗮 𝗶𝗻 𝗮 𝗯𝗼𝗼𝘀𝘁 𝘁𝗼 𝘀𝘆𝗻𝘁𝗵𝗲𝘁𝗶𝗰 𝗹𝗲𝘁𝗵𝗮𝗹𝗶𝘁𝘆 𝗽𝗹𝗮𝘆 Fresh Phase 2 data are adding weight to Ideaya IDEAYA Biosciences case for a targeted therapy it believes could be a first-in-class treatment option for certain …Yujiro S. H. https://lnkd.in/d-wViywi

Choosing the right protocol is essential, especially when dealing with limited sample numbers and quantities. Explore the best way to accomplish this in the field of phosphoproteomics by referring to the STAR protocols paper by Claire Koenig and Ana Martínez del Val from the Jesper Velgaard Olsen Lab. In this paper, they have condensed their guidance, employing magnetic particles from ReSyn Biosciences, to establish a streamlined, modular, and semi-automated workflow. This workflow was then applied to limited biological samples using the sensitive Whisper methods on the Evosep One. #proteomics #tmt #lcms #automation

“Development of an End-to-End Scalable Purification Platform for #ExtracellularVesicles” unifies both upstream and downstream process development via our ongoing Sartorius collaboration to pioneer advanced therapeutic #exosome production. This work employs Sartorius’ efficient, integrated downstream process technology, as well as novel analytical methods, to assay quality of product EVs. 📊 Download the poster to gain insight on state-of-the-art methods via this study’s thought co-leadership: https://lnkd.in/ePFFGshA #exosomes #microvesicles #celltherapymanufacturing #advancedtherapies