NutraIngredients’ Post

🌾A revolutionary discovery in Rice Research to address the increasing prevalence of diabetes.🌾 🍚. International Rice Research Institute (IRRI), a #CGIAR Research Centre, have identified the genes accountable for low and ultra-low glycemic index (GI) in rice. 🍚. According to International Diabetes Federation, there were 537 million people with diabetes in 2021. This is expected to go up 47% by 2047 Many rice varieties have GI ranging from 70 to 92, which is not considered healthy for people with diabetes. The ultra-low GI has a level of 44. 🍚. This scientific advancement results from an extensive collaboration between IRRI scientists at the organization's global headquarters supported by the Philippine government and the IRRI South Asia Regional Centre in Varanasi. 🍚. Previously, IRRI pinpointed two low glycemic index (GI) Philippine strains, IRRI 147 and IRRI 125, which were introduced in the Philippines as salt-tolerant varieties. In a cohort study involving clinical validation with human volunteers, IRRI 147 displayed a GI value of 55, while IRRI 125 exhibited a GI value of 51.1. 🍚. Dr. Ajay Kohli , serving as the Interim Director General of IRRI, emphasized that these research breakthroughs offer essential health benefits and significant market potential. He also mentioned that the ultra-low GI variety will be ready for the market within two years. #6thInternationalRiceCongress #Globaleffort #Riceforfuture

For the first time in Malaysia, a study results on the Anti-SARS-CoV-2 and Anti-inflammatory Activities of Marantodes pumilum Aqueous Ethanolic Standardized Extract (SKF7®) led by Dr. Mohd Ridzuan Mohd Abd Razak from the Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health will be presented at the 24th NIH Scientific Conference on August 22nd and 23rd, 2023. The in-vitro study demonstrated that the M. pumilum standardized extract, SKF7®, exhibited anti-SARS-CoV-2 activity against both the WT Wuhan and the omicron SARS-CoV-2 infections. This suggests its potential for further evaluation as antiviral and immunomodulatory agents. IMR will publish the detailed study results. SKF7® is a registered and patented standardized extract of Labisia pumila owned by Medika Natura Sdn Bhd. Please visit https://lnkd.in/gc5HrSjm for further details of the event. #covid19 #antiviral #immunotherapy #botanical #clinicalresearch #malaysia

SAVE THE DATE! This GA #eSeminar on “Clinical Testing of Herbal Medicinal Preparations in Africa” is organized by the African Research Network (ARN) of the Society for Medicinal Plants and Natural Products Research (GA) and the PharmaConnect Africa (PCA). This eSeminar will bring together leading experts in the field of herbal medicinal research to discuss the clinical testing of herbal medicinal preparations in Africa. The seminar will showcase the clinical development of HMPs in Africa, by presenting the preclinical research and the development of a phase III clinical trial design of a HMP and the challenges and opportunities in this field. Speakers and topics are: 1. Prof. Sylvin Ouedraogo (IRSS, Burkina Faso): Prof. Ouedraogo will present the preclinical dataset of a herbal treatment for sickle cell disease. This presentation will provide insights into the scientific data supporting its therapeutic potential. 2. Dr. Merlin Willcox (University of Southampton, UK): Dr. Willcox will deliver a “How to” lecture on the development of a phase III clinical trial design. Using the example of the herbal treatment for sickle cell disease, he will guide the audience through the critical steps and considerations in designing a clinical trial for an HMP. 3. Prof. Motlalepula Matsabisa (University of the Free State, South Africa): Prof. Matsabisa will discuss the “Challenges and Opportunities on Clinical Testing of Herbal Medicinal Preparation in Africa”. His presentation will shed light on the unique hurdles and prospects encountered in the African context. The objective of this eSeminar is to foster a deeper understanding of the clinical testing of herbal medicinal preparations in Africa, promote knowledge exchange, and stimulate further discussions in this field. https://lnkd.in/eRjXpaiS

📣📣 Don't miss on the new eSeminar “Clinical Testing of Herbal Medicinal Preparations in Africa”, co-organized by the African Research Network of the Society for Medicinal Plants and Natural Products Research (GA) and PharmaConnect Africa (PCA). Get ready to join this free and open seminar on 🗓️ April 30, 2024 at ⏰ 17–19 p.m. CEST.   🔗 Click here for the Zoom registration → https://lnkd.in/ePqfHDhX   🌏 Do you want to learn more about clinical testing of herbal medicinal preparations in Africa? This eSeminar will bring experts in herbal medicinal research to discuss the journey of HMPs from preclinical research to phase III clinical trial design, and explore the challenges and opportunities in this field.   👨🔬 Speakers and topics: Prof. Sylvin Ouedraogo (IRSS, Burkina Faso): Unveiling the preclinical dataset of a herbal treatment for sickle cell disease. Dr. Merlin Willcox (University of Southampton, UK): A step-by-step guide on developing a phase III clinical trial design Prof. Motlalepula Matsabisa (University of the Free State, South Africa): Insights into the challenges and opportunities of clinical testing of HMPs in Africa.   For more information click here: https://lnkd.in/eAKJ7evc #HerbalMedicinalPreparations #Africa #ClinicalTesting #GA_AfricanResearchNetwork #PharmaConnect_Africa

https://lnkd.in/gyfJDt5h Therapeutic Value Of Dragon Fruits-An Overview

#SSETS #SharingMyResearchOnSSETS I will be sharing one of my original research findings with you this week titled; ''Effect of Combination Therapy of Garcinia kola seed and Vitamin E in Acetaminophen Induced Hepato toxicity and Oxidative Stress in Albino Rats.'' Acetaminophen is one of the available drugs that is been abused by its usage. Though, it is used to treat fever and pains. It has been reported to exhibit toxic side effects when taken in overdoses. In this study, it was used to induced hepato toxicity and oxidative stress in albino rats. On the other hand, Garcinia kola seed aqueous extract and Vitamin E were given to these rats before the inducement in singly and combined treatment formulations/ doses and duration. It was observed that the combined form of pretreatment showed no significant synergistic effect in ameliorating the hepato toxicity and oxidative stress compared to the singly pretreatment with either Garcinia kola seed or Vitamin E.Therefore combining Garcinia kola and Vitamin E may lost its ameliorative and protective effect as seen in this induced acetaminophen albino rats implying that Garcinia kola seed and Vitamin E should not be taken in a combined form. This activity is being made possible by Foreign, Commonwealth and Development Office, Lancaster University, British Council, National Universities Commission (NUC), Rivers State University and Dr Mina Ogbanga (CFRM). I am super grateful. #SSETS #SharingMyResearchOnSSETS

NATURAL HONEY WITH GLIBENCLAMIDE IMPROVES HYPERGLYCAEMIA BETTER THAN GLIBENCLAMIDE ALONE ___ Getahun Tsegaye Dibaba from the Addis Ababa University, Ethiopia presented a paper entitled “Effect of natural Honey on biochemical markers in STZ-induced diabetic mice”   Their study concluded that consuming natural honey with glibenclamide improves hyperglycaemia, and causes a change in lipid profile than consuming glibenclamide alone. To learn more about their study, kindly refer to the summary in the attached infographic.

Artemisia annua stems and leaves were commonly used to treat malaria in ancient times. Modern Chinese medicine analysis found that artemisia annua stems and leaves can treat malaria because artemisinin is rich in them. Artemisinin is one of the best drugs to treat malaria resistance and has been recognized internationally. The traditional process is to #extract artemisinin from gasoline, which has some problems such as low yield, high cost and safety risk. In the past, China's artemisinin extraction #technology was relatively backward, and China's artemisinin drugs only accounted for 0.5% of the international market share. In recent years, with the development of supercritical carbon dioxide fluid #extraction technology in China, the market share of artemisinin drugs in China is increasing. The #practice from small trial to pilot trial and then to large-scale production has proved that the supercritical CO2 extraction process can be used for the production of #artemisinin, and the quality of the #drug meets the Chinese drug standard. 🤝 If you are interested in this activity, please feel free to contact us. 📮Email:[email protected] 🔗Web:https://www.xs-purify.com/ #ChineseMedicine #malaria #ChineseMedicine #Artemisiaannua #Artemisinin #Extraction #Supercritical #Therapeutic #Green #Saving #NoResidue #NoHazard

Discover the wealth of traditional uses, taxonomy, phytochemistry, and pharmacological properties of Manilkara zapota in our latest review! 📚 entitled "A systematic review on traditional use, phytochemistry and pharmacological activities of Manilkara zapota" Findings 🌿 Exploring the Potential of Manilkara zapota in Herbal Medicine 🌿 We've identified 21 natural compounds from Manilkara zapota, including alkaloids, tannins, terpenoids, and flavonoids. Explore its diverse pharmacological activities, from antimicrobial to anti-inflammatory properties. Our review offers valuable insights and recommendations for future research in drug development. Join us as we uncover the therapeutic potential of this remarkable plant! 🌍💡Doi- https://lnkd.in/gvabxVT3

The Power of Three Kingdoms!   Lungwort (Lobaria pulmonaria) is an epiphytiuc lichen that looks like a leaf, but is made up of three organisms from three kingdoms living together—it consists of a fungus (ascomycete), a green algae and cyanobacterium…wrap your brain around that!     It was named because of its resemblance to lungs, and in accordance to the herbal “doctrine of signatures”, was used for afflictions of the lungs in herbal medicine.   Lungwort is widely distributed throughout the world, present in Europe, North America, Africa and Asia; mostly in damp habitats.    Not only has it been used as a medicine, but in foods, as an ingredient in brewing, the manufacture of perfumes, to produce an orange dye for wool, and for leather tanning.   Lungwort is considered GRAS in the US as a flavoring.   As it is highly sensitive to pollution, and sulfur dioxide in particular, its populations have declined significantly, especially in lowland areas.   Lungwort has a long history of use in herbal medicine, and has been used for various lung afflictions, such as asthma, tuberculosis, and pneumonia.   Lungwort has also been used for eczema and hemorrhage, as an antiseptic, and anti-inflammatory.   Through scientific investigation Lungwort has been found to have anti-inflammatory, antiproliferative, antimicrobial, antiulcer, GI-protective, anti-acetylcholinesterase and antioxidant activities.   New applications are being investigated in their use for the nontoxic production of silver nanoparticles with pharmaceutical applications.    #MedicinalPlants #Ethnopharm #Ethnobotany #MedicinalPlants #GRAS #asthma #pollution   **This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician.