National Institute of Allergy and Infectious Diseases (NIAID)’s Post

Did you know there is a bacteria that is known as Fusobacterium nucleatum that lives in the human mouth and is rarely found elsewhere? Interestingly though, in cases of cancer of the colon or the rectum, this same bacteria is found in tumors in the gut, where they help cancer cells escape from the immune system and spread to other parts of the body. A new study by a group of researchers from the Fred Hutchinson Cancer Center in the U.S. has identified a distinct subtype of the bacterium that’s found in relatively greater quantities in colorectal cancer tumors. The study’s findings could be used in future to develop tests to detect CRC early and develop targeted treatment options ✍ Sayantan Dutta https://newsth.live/GsTTB1

Researchers developed a new urine test called MyProstateScore2.0 (MPS2) that can identify aggressive prostate cancer, potentially reducing unnecessary biopsies for men. This breakthrough test analyzes 18 genes linked to high-grade prostate cancer in urine samples. Studies showed it successfully identified cancers needing immediate treatment, while nearly perfectly ruling out slow-growing, harmless ones. MPS2 has the potential to significantly reduce unnecessary biopsies. PSA testing alone avoids 11%, but MPS2 could avoid up to 41%. This is a major benefit as biopsies are invasive and uncomfortable. MPS2 is currently available through a spin-off company specializing in commercializing this test. #CancerResearch #Immunotherapy #UniversalCancerVaccine #FundingTheFuture #YouCanHelp  #HopeForACure #Cancer #Hope  #FYP #Explore

Targeting the basis of CD8 T cell recognition of tumour antigens by forcing the expression of MHC-I in ovarian cancer cells, can increase the efficacy of several cancer therapies...find out more in this very exciting research article! One of the projects I have been working on during the past years (pandemic included)... 🤓 https://lnkd.in/d6hrKur6

The research on how removing old, senescent immune cells can help manage the progression of lung cancer. This approach offers promising insights into more effective cancer therapies. Thanks to Sumeet Pandey, PhD, and Samir Morsli #happiesthealth #futureofhealth https://lnkd.in/dG_rAze7

Check out this insightful article in Happiest Health by Dr. Chandandeep Kaur on the role of aged immune cells in cancer and the potential of clearing them out for effective cancer treatment. The summary is derived from paper published in Cancer Cell (https://lnkd.in/dCETXJam) showing how clearance of senescent macrophages ameliorates tumorigenesis in KRAS-derived lung cancer! https://lnkd.in/dUGXbZ7S

About the PSA Test: 🔍 Prostate-specific antigen (PSA) is a protein made by cells in the prostate gland (both normal cells and cancer cells). PSA is mostly found in semen, but a small amount is also found in blood. 📈 Elevated PSA levels can be an indicator of prostate cancer; however, a high PSA level can sometimes be caused by reasons unrelated to #prostatecancer, such as age, prostatitis, or prostate enlargement. ➡️ A PSA level > 10 ng/mL corresponds with a 50% prostate cancer risk. Reference: American Cancer Society https://ow.ly/rfOz50PI0XO #menshealth #PCSM #peaceoutprostatecancer

We believe a key to improving cancer treatment outcomes is to redefine and reset the tumor microenvironment. Recent research has shown that targeting the tumor microenvironment may enhance the effectiveness of therapies and reduce resistance to standard therapies. By modulating the complex interactions between cancer cells, immune cells, and other components of the tumor microenvironment, we believe new strategies, such as Olvi-Vec, may be successfully developed to fight cancer. #cancertreatment #stage4needsmore #drugresearch #drugdevelopment

TMB (tumor mutational burden) is a marker of how many mutations are found in a particular cancer. It is a predictive biomarker that gives information about whether immunotherapy might be useful in treating that cancer. Learn more about TMB and its impact on your treatment options at https://lnkd.in/ebetwrxU #linkinbio #knowyourbiomarker #fastfacts #colorectalcancer #TMB #tumormutationalburden

Barrigel - symmetry, stability, safety. Customized spacing without time constraints. Because control matters.