National Institute of Allergy and Infectious Diseases (NIAID)’s Post

11 clinical trials that will shape medicine in 2024: Nature Medicine asked leading researchers to name their top clinical trial for 2024, from base editing and a vaccine against HIV to artificial intelligence tools for lung cancer and patient triage. https://lnkd.in/ewugcbMQ Which one are you most excited about? 💡 It has to be Enhertu for me; a Her2-ADC that made us all think twice when it was shown to work in Her2-low breast cancer patients. We need to do more to make sure that all patients who can benefit are eligible for #targetedtherapy → biomarkers of response need to be looked at in the early #drugdevelopment / #preclinicalresearch settings!

For sickle cell disease, cardiac disorders, HIV, cancer, neurodegeneration, diabetes and fibrosis (e.g., cystic fibrosis) : VincoAI, successfully generated a 7mer peptide, VHDAC-46-7MEROL, that targets the active site of HDAC3 by computational peptide-protein docking simulations. Although these in-silico results support VincoAI peptide potential as HDAC3 blocker, in vitro and in vivo validation is still needed. #sicklecelldisease #hdac #ai #vincoai #vincogen #fibrosis #cysticfibrosis #hiv #diabetes #neurodegeneration #cancer

📰Published in Blood Advances, this multicentric retrospective study involving 1⃣1⃣ centers from 4⃣countries was designed to evaluate the impact of MYC rearrangements (isolated or w/ BCL2 and/or BCL6 translocations) on clinical features & outcome of HIV-associated LBCL READ➡️https://lnkd.in/ef8w5BQJ #HIV #Lymphoma #cancer #bloodcancer #blooddisease

What is Flow Cytometry? Understanding the Importance of Flow Cytometry: Flow cytometry is a high sensitivity laboratory technique that plays a crucial role in diagnosing and staging leukemias and lymphomas, and for monitoring the treatment progress of cancer patients. Flow is also critical for monitoring infectious diseases (like HIV) and auto-immune disorders (like Lupus). To read our full article, please go to: https://lnkd.in/ezyVmnns #acupathlabs #laboratory #laboratoryprofessionals #flowcytometry #cancerawareness #cancer #cancerprevention

Join us at #AACR24 where we, together with our collaborators, will deliver presentations covering a range of topics, including the use of comprehensive #genomic and #transcriptomic analysis in patients with blood and solid cancers. We'll also discuss RNA-based models for TLS prediction in lung and pancreatic cancers, a transcriptomic-based approach to distinguish sarcomatoid features in kidney cancer and the impact of race and HIV status on the genetic landscape of #DLBCL patients in southern Africa. https://lnkd.in/eRaH-dDd

Did you know? Cervical cancer is most frequently diagnosed in women between the ages of 35 and 44 globally. Recognize the importance of early detection and timely treatment for cervical cancer by prioritizing regular screenings, fostering a vital path to long-term well-being. #ADSCC #HPV #HIV #CervicalCancer #WomensHealth #Cancer #Diagnosis #EarlyDiagnosis #Prevention #CervicalCancerPrevention #EarlyDetection #CervicalHealth

Women living with HIV are 6x more likely to develop cervical cancer. Union for International Cancer Control (UICC) #WorldCancerDay #CloseTheCareGap #cancer #cancerawareness #WorldCancerDay2024 #mgchri #mgcancerhospital #cancerawareness

Did you know 2,300 men in the UK are diagnosed each year with testicular cancer? Men's Health shouldn't only matter on International Men's Day, it should be important every day. In our blog, we discuss the symptoms of testicular cancer and what you should do if you happen to have any of the symptoms. Read more here... 💻 https://lnkd.in/e6K-SSkm #internationalmensday #wellness #supportingmalewellbeing