LCRC by UHasselt - Jessa - ZOL’s Post

Partnerships are key to scaling AI in Medicine education and training, which is critical if we are to realize the benefits of AI as a transformative technology in medicine and healthcare.

So this happened in late August. Our research team of 5 - 3 of us made it to the night (Martin Donnelley, Kaye Morgan, and me) won the “Excellence in Interdisciplinary Scientific Research” award at the 2023 Eureka Prizes award ceremony, for our work with Australian company 4DMedical in developing their X-ray Velocimetry (XV). This is a lung health imaging system the team focused towards the needs of people living with cystic fibrosis (CF) to measure airflow in all parts of the lung, and during the breath cycle. No other lung health test can do this. Andreas Fouras and Steve Dubsky (originally Monash Uni) were the two other members of the team, and it was Andreas who conceived the idea to apply an aeronautical flow imaging technique - particle image velocimetry - to measuring lung motion so that airflow could be measured throughout the lung, and he led the successful development work into a startup company and then to a commercial product. The annual Eureka Prizes are the premier comprehensive scientific awards in Australia, and have been running for 33 years. We are all pretty pleased, and if you scroll down at the first link you’ll find all the category winners, and us. At the second link you’ll see some amazing and cool science that has been going on: https://lnkd.in/gy3XRQsh and https://lnkd.in/g4ny2nQd XV imaging is the first new way to measure lung health since CT began to be applied to lung structure imaging in the 1970’s. It specifically measures lung motion, not structure, and so airflow can be derived throughout the lung. The standard lung health tests that many people will know of (spirometry, otherwise known as “blowing tests”) can’t be used in children under 6 - when disease may be developing -as it requires proper control and specific effort. The 30-sec fast-summary movie that was shown on the night about our work is here: https://lnkd.in/g_Mkta9R Our research in Adelaide has been focused on developing a lung gene-correction therapy for children born with CF, and we knew that a technique like this was the only way to know that a treatment actually had a useful effect, by being able to detect regions of lung airflow that were worsening with CF disease, or improving with genetic or other treatment. So in late 2009 I got together with Andreas Fouras while we overalapped at the SPring-8 synchrotron in Japan and helped Andreas as he led our team to crystalise, develop and completed his innovative idea about measuring lung motion using aeronautics principles. There’s lots of easy to digest information about XV at the 4DMedical website if you are interested to know more. The publications list has been recently updated. If you are a science nerd and would like finer detail message me or email to [email protected] (And for disclosure, I have purchased shares in 4DMedical) https://4dmedical.com/

Love this video of them, Drs. Katalin Karikó and Drew Weissman and see how their persistance and being passionate about RNA, Immunology and develping vaccines led to a vaccine development which helped us all to survive COVID-19 pandemic and have our elder parents and loved ones still arround, where many lost theirs due to lack of fast vaccine availability in their country! I congratulate them both on winning The Nobel Prize. They are role models to many of scientists like us, keep pushing bonderies and not giving up when you are passionate about your field of research! #cancerresearch #percisionmedicine #translationalresearch #cancerearlydetection #proteomics #multiomics #pushingboundries

Just 8 days to PMWC 2024: New Federal Programs Driving Transformative Health Breakthroughs January 24, Santa Clara Convention Center This session, part of Track 4, will highlight innovative federal initiatives in precision medicine, featuring leaders from federal science and tech agencies: 🚀 ARPA-H is spearheading the charge against complex health issues with targeted funding. By empowering Program Managers to lead bold research strategies, ARPA-H is sparking multidisciplinary collaborations for breakthroughs in biomedical research, with the potential to transform both individual and population health. 🌐 The CHIPS & Science Act, coupled with the Executive Order on Biotechnology & Biomanufacturing Innovation, is creating a synergy of interdisciplinary progress. These initiatives are designed to amplify research and commercialization in crucial areas such as climate, energy, and health, through evidence-based and outcome-focused approaches. 🤖 NSF and NIST are at the forefront of the technological revolution, driving AI, biotechnology, and computational research forward. This includes the development of AI-driven bioproduction, advanced gene editing techniques, and fundamental studies that could revolutionize predictive modeling in biological systems. More sessions at New Frontiers of Precision Medicine: PMWC 2024 Award Ceremony Luminary Honoree Geoff Ginsburg, NIH Fireside Chat: Geoffrey Ginsburg, AllofUs/NIH, and Keith R. Yamamoto, University of California, San Francisco AI-driven Advances in Precision Medicine (PANEL) Chair: Sharat Israni, Bakar Institute, UCSF Suzanne Tamang, Stanford Colleen Clancey, UC Davis Nevan Krogan, UCSF Laura Erdman, University of Toronto Precision Medicine in New Research Frameworks (PANEL) Chair: Regis B. Kelly, UCSF Joe DeRisi, UCSF Luke Gilbert, UCSF Prachee Avasthi, Arcadia Science Living Therapeutics for Precision Medicine (PANEL) Chair: Michelle Hermiston, UCSF Peter Marks, FDA Wendell Lim, UCSF Liora Schultz, Stanford AI and Precision Medicine: Navigating Equity and Social Justice Challenges (PANEL) Chair: Hank Greely, Stanford Ziad Obermeyer, UC Berkeley/ Dandelion Health Sara L. Ackerman, UCSF https://lnkd.in/gjUDr3fe #PMWC24 #PrecisionMedicine #HealthBreakthroughs #FederalPrograms #ARPAH #CHIPSandScienceAct #Biotechnology #Biomanufacturing #AI #LivingTherapeutics #Equity #SocialJustice #GeoffGinsburg #NIH #UCSF #Stanford #UCDavis #universityoftoronto #FDA #ARPAH #BiomedicalResearch #MultidisciplinaryCollaborations #TransformativeHealth #CHIPSandScienceAct #ExecutiveOrder #InterdisciplinaryProgress #ResearchCommercialization #NSF #NIST #TechnologicalRevolution #ai #Biotechnology #ComputationalResearch #AIbioproduction #GeneEditing #PredictiveModeling #BiologicalSystems #UCBerkeley PMWC - Precision Medicine World Conference

'The' publication of my PhD is now out - it shows that impairments in a specific type of navigation behaviour might be one of the earliest diagnostic signals for Alzheimer's disease, even before memory loss. ⛵ This form of navigation - known as path integration - is a common species-wide behaviour and is akin to "dead-reckoning" used historically by mariners to navigate oceans 👓 We used virtual reality headsets to test this, which in another recent publication from my time with Hugo Spiers was found reflective of real-life navigation: https://lnkd.in/eutGjEE7 ♀ ♂ The results were gender-specific, highlighting the need for personalised diagnostics 🔍 Look out for two more publications in the works with Dennis Chan and P. John Clarkson where we investigate how to translate this proof-of-concept research into usable, scalable, and culture-fair clinical tools, in part through my ongoing Schmidt Science Fellows research 📖 Read more in press releases and news coverage here https://lnkd.in/ejSTfA-V https://lnkd.in/etr_Sm3Z https://lnkd.in/epjdnhvb UCL University of Cambridge Alzheimer's Society

This year at PrecisionMed Exhibition & Summit (PMES) 2024, we are launching #PrecisionGenQuest, a competition dedicated to PhD students, inviting them to present their research about Precision Medicine. The competition will reflect the themes of this year’s PMES main stage which are: Healthy Populations, Lifestyle Intervention and Disease Prevention, Clinical Genomics, and AI in precision medicine. Each theme is represented by an Ambassador to champion the submissions. 1. Healthy Populations - Dr. Julie Decock 2. Lifestyle Intervention and Disease Prevention - George P. Patrinos 3. Clinical Genomics - Mohamed Nagy . 4. AI in precision medicine - Dr. Min Sung Park The event’s panel of judges, composed of leading experts and luminaries within the scientific community, will evaluate the submissions based on criteria such as originality, clarity of presentation, scientific merit, and potential impact within the relevant field. Insights and innovation will unite on the event’s main stage on May 8th where the top two abstracts per theme will be featured and 1 winner in each theme will be awarded. Learn more about it and Submit your abstract today! https://lnkd.in/d8D7pzPH #PrecisionMedicine #Research #PersonalisedMedicine #HealthTech #Genomics #AIinPrecisionMedicine #PMES24 hashtag #PMESUAE24

𝐍𝐞𝐰 𝐛𝐞𝐠𝐢𝐧𝐧𝐢𝐧𝐠, 𝐒𝐚𝐦𝐞 𝐠𝐫𝐞𝐚𝐭 𝐭𝐫𝐚𝐝𝐢𝐭𝐢𝐨𝐧 📢 💼🔬🧬 Science remains the tradition that drives innovation, be it in Academia, Industry or in Government. It's a brand new beginning for me at the National Center for Advancing Translational Sciences (NCATS), NIH! Happy to share that I’ve started as a Postdoctoral Research Fellow and grateful to join Dr. Xia Menghang in the Tox21 Program at the Division of Preclinical Investigation. This transition is exciting as I will be engaging in translational work, advancing from my previous doctoral work in academia. NIH... Turning Discovery into Health

We just released the new agenda for our 15th World Conference on Targeting Mitochondria

I took the vaccines, and I thanked them for their work. They deserved their Nobel prizes indeed. It is also worth pointing out that Dr. Karikó was demoted (back in 1995) by the same institution that praised their work below. This was unkind. Aside from the points above, I also noted the lines about submitting grants before midnight, talking to colleagues at 2 and 3 AM, among others. These were perhaps good strategy to achieve successes for them; ones that worked in the past. However, these practices are very draining, not sustainable, and not reflective of a good work-life balance. Over times, these types of actions become normalized and that's how we end up with stories of graduate students sleeping in lab over NYE, advisors who abuse their grad students, students who become depressed, and even students who ended their lives. Let me be clear, to each their own. I'm not trying to tell you to do one thing--after all, being told to do something a certain way is not on the top of the list of things scientists like to do. Still, I invite fellow scientists to really pay attention to the messages we communciate to future generations, particularly aspiring scientists who may not be well equipped with the drain and anguish that we often hear in academia. For aspiring researchers, it is important to have good boundaries between work and lives. Unless you live to work, work is not your identity. Remember, we only have one body and one life. Institutions will go on.

Are you interested in learning more about the science behind TCR-epitope prediction models? Join our CTO, Pieter Meysman, in the upcoming seminar organised by AIRR Community! 👨🏫 Seminar Title: On the application of TCR-epitope prediction models 📅 Date: September 28th 🕒 Time: 16:00-17:30 CET 🏢 Venue: Zoom (https://lnkd.in/emF63a8R) Key Seminar Highlights: 🔍 TCR Sequence as the Key: The T cell receptor (TCR) sequence and all the information it contains to recognise its target epitope. 🔍 Machine Learning in TCR-Epitope Prediction: The use of ML and the challenge of inferring epitope targets from TCR sequences within specific contexts. 🔍 Identifying Epitope-Specific T-Cells: How TCR-epitope prediction models can be applied to identify epitope-specific T-cells in complete repertoire data. 🔍 Future Advances in Immunology: What the milestones expected in the field are, particularly in addressing the unseen epitope prediction problem. Don't miss this free opportunity to hear from one of the leaders in the TCR field. Find out more at: https://lnkd.in/eFVj_sfA