IPHA’s Post

We're looking forward to participating in the European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe 60th anniversary conference "Today, Tomorrow, Together for Public Health" where Baron-Papillon Florence will discuss the value of vaccination and how we can unlock the potential of novel therapies #EDQM60

One of the biggest issues facing the recruiting of patients into clinical trials is that of lack of awareness that trials exist. I think the industry has really missed a trick over the last few years, as throughout 2020 the whole world knew there were clinical trials taking place - for Covid vaccines. Capitalizing on that extreme amount of awareness should have been something we could do to keep up the momentum and make people aware that there are trials for all manner of diseases and conditions, as well as those related to a global pandemic. I’m certainly hoping there isn’t another Covid-style event on the horizon. But I’d love to see primary care physicians taking more of a lead to encourage their patients to investigate trials they may qualify for - with doctors obviously being in the position of trusted advisor who should also be best-placed to understand eligibility criteria and be able to explain what’s involved in trial participation. #patientrecruitment #clinicalresearch #clinicaltrials

For the past two days I attended the IABS meeting on "The Role of Real-World Evidence for Regulatory and Public Health Decision Making for Accelerated Vaccine Deployment" and we explored and discussed the possibility / the conditions that would be required to deploy a vaccine with more limited clinical trial data and a greater reliance on the generation of real-world effectiveness during use of the vaccine in a public health response. For safety, the question had already been asked. Do phase III trials add any additional knowledge of safety which justifies their large cost?

There is no medicine that is safe for everyone   Having spent a significant portion of my life in Pharmacology and the research and development of Medicines I can say with some authority that there is no medicine that is safe for “everyone”. All medicines have known side effects for a proportion of the general population. I went to see my doctor for my biannual check-up and he said your blood chemistry results and physical status for a 76-year-old are remarkable given you treat your body like Jucy rental car ,but your blood pressure is a bit on the high side so he prescribed a drug to reduce my blood pressure.   I checked out the drug’s potential side effects which were shortness of breath, swelling of the throat and legs. I nearly chocked to death eating a steak at a restaurant and overnight I had elephant legs. Once I stopped using the drug It took ten weeks for my body to recover from the side effects of a clinically approved prescription drug. The reality is that no Drug or Vaccine is safe for “everyone.” There are side effects for some.   Recently a Coroner attributed a New Zealand’s man’s death due to a rare side effect of the Covid Vaccine.     https://lnkd.in/gHtwHxqe   The European Medicines Agency (EMA) reported that 11 448 people have died in the EU following COVID-19 vaccines. 8 368 following Pfizer BioNTech vaccinations (which is 1 345 more deaths in 2022). 1 579 following AstraZeneca vaccinations. 1 161 following Moderna vaccinations. 339 following Janssen vaccinations. 1 following Nuvaxovid vaccinations. 0 following (inactivated, adjuvanted) Valneva vaccinations. As of 10 April 2023, a total of 50 648 deaths caused by ‘COVID vaccines’ had been reported in EudraVigilance – broken down by disease (heart conditions, central nervous system disorders, etc.). Vaccinating people at risk of dying of Covid makes sense. But should the NZ Government have mandated Covid vaccinations for a whole population for whom for most Covid was not a life-threatening disease and that for some could present serious adverse healthcare outcomes without as with other medicines advising the general population about the risks of taking the vaccine and giving them a personal choice. To be vaccinated or not? This is a travesty of unparalleled moral and ethical proportions. Sir Ray Avery                  

@NEDLAC_SA Greater trust for evidence-based healthcare interventions such as vaccines should be developed rather than relying on enforcement. This is one of the key take-aways in the close out Covid-19 Report launched today at the Nedlac Annual National Summit. #Nedlacsummit28

GHC COVID-19: Review of 5 Vlogs - Prof #Karafilakis (#Vaccine #Confidence), Prof #Altmann (#Long #COVID), Prof #Lopalco (COVID #Vaccines), Prof #MartinonTorres (COVID in #Children) PLUS #Future #Pandemics. See: