Initiative on Crohn and Colitis (ICC) reposted this
MD, PhD candidate | Clinical Research Fellow dept. Gastroenterology and Hepatology at Mount Sinai Hospital Toronto
Happy to share our two open-access research papers in the field of postoperative recurrence in Crohn's disease, published in GIE: Gastrointestinal Endoscopy, VideoGIE, and iGIE and American Journal of Gastroenterology! https://lnkd.in/eX4ZYWAy 📖 The modified Rutgeerts' score is currently used to assess for the assessment of endoscopic postoperative recurrence (ePOR) in Crohn’s disease (CD). Two new endoscopic scores (updated Rutgeerts' score and REMIND score) have been proposed for the assessment of postoperative recurrence in Crohn's disease. However, the additional value of these scores is still unclear. ❔ This study assessed the interobserver agreement of the current (mRS) and new endoscopic scores for ePOR in CD 🆕 The interobserver agreement of the mRS is substantial. Similarly, the interobserver agreement is substantial for the updated Rutgeerts’ score. According to the REMIND score, the interobserver agreement was substantial for lesions in the neoterminal ileum, whereas only moderate for anastomotic lesions. 🔑 Since therapeutic decisions in clinical practice are based on these assessments and these scores are used as outcome measure in clinical studies, further improvement of the interobserver agreement is essential. https://lnkd.in/eA67kx9d 📖 The prognostic value of the modified Rutgeerts score (mRS) in patients with Crohn's disease needs to be further elucidated. ❔ This study assessed the prognostic value of the mRS for long-term outcomes after primary ileocecal resection in patients with CD. 🆕 The increasing mRS corresponds closely with the risk of surgical and clinical recurrence. An index mRS ≥ i2b is associated with surgical recurrence, an index mRS ≥ i1 is associated with clinical recurrence, and i1 or i2b with progression to severe endoscopic recurrence. 🔑 These results support tight monitoring of disease activity and treatment optimization in patients with ileal lesions and a more conservative management in patients with anastomotic lesions. Annemarie de Vries Od van Ruler C. Janneke van der Woude Laurents Stassen Initiative on Crohn and Colitis (ICC) Initiative on Crohn and Colitis Surgery (ICC-S)
