Calling all Licensed Pharmacists with oncology experience who are ready for a change! HJF is hiring a Clinical Pharmacist to support the Murtha Cancer Center Research Program (MCCRP) & Hematology Oncology clinics located at the Walter Reed National Military Medical Center, in Bethesda, Maryland. This is a great opportunity to make a difference, collaborate with other pharmacists, and expand your pharmacy expertise. Check out the job on our careers page! https://lnkd.in/eK_6yQv2 #HJF #Military #Medicine #Oncology #Pharmacist
The Henry M. Jackson Foundation for the Advancement of Military Medicine’s Post
More Relevant Posts
-
ASCO 2023 - New Data Highlights Three Studies Showing The Impact Of Vitrakvi On Long-Term Efficacy & Safety In Adult And Pediatric Patients Read more: https://bit.ly/3RkkBjO #OncologyInspired #PatientInspired #PrecisionOncology
To view or add a comment, sign in
-
𝐑𝐚𝐫𝐞 𝐏𝐞𝐝𝐢𝐚𝐭𝐫𝐢𝐜 𝐃𝐢𝐬𝐞𝐚𝐬𝐞 𝐏𝐫𝐨𝐠𝐫𝐚𝐦 𝐒𝐞𝐭 𝐭𝐨 𝐒𝐮𝐧𝐬𝐞𝐭 During a coffee chat organized by the Biotechnology Innovation Organization, I-ACT for Children's Chief Medical Officer AJ Allen, along with fellow panelists Karin Hoelzer, Maynard Friesz, and Jamie Sullivan, discussed the importance of the Pediatric Priority Review Voucher (PRV) program. They talked about the program's impact on drug development for rare pediatric diseases and the need for its continued authorization. The panelists highlighted the significance of the PRV program in motivating pharmaceutical companies to invest in research and development for treatments for rare pediatric diseases such as Spinal Muscular Atrophy, Duchenne muscular dystrophy, cystic fibrosis, various pediatric cancers, rare inborn errors of metabolism, lysosomal storage disorders, immunological disorders, and many more. The panelists also stressed the importance of raising awareness about the PRV program and advocating for its extension beyond September 30, 2024, the date when the program is set to sunset. They discussed the potential consequences of a lapse in authorization, including delays in the development of life-saving treatments for children with rare diseases. The panelists agreed that the PRV program is a crucial tool in advancing research and finding cures for rare pediatric diseases, and they are committed to working together to ensure its continued success. Learn more about the PRV program: https://lnkd.in/eJUZQRua. #orphandrugdevelopment #pediatricresearch #PRV
Primer on Rare Pediatric Disease (RPD) Priority Review Vouchers
https://www.youtube.com/
To view or add a comment, sign in
-
Reflections on Rare Disease Day 2024: As a pediatric neurologist, I spent my entire post-graduate career involved in the diagnosis and management of children and adults with both neuronopathic and non-neuronopathic lysosomal storage disorders. For those without brain involvement I had access to a variety of life saving medications that transformed the lives of these patients (e.g. Gaucher has 5 FDA approved therapies). However, I would then (usually within the same day) meet with families of children with the neurodegenerative forms of these disorders and all I had to offer was symptomatic care. Symptomatic care is critical in addressing their quality of life; however, it did not alter their trajectory enough to prevent disease progression. I've had countless end of life discussions in my clinical career; and I have sat at the bedside of dying children and attended too many funerals. In recent years, I had renewed hope as various industry sponsors developed therapies that could potentially cross the blood brain barrier to treat the brain. This is an important moment for rare neurogenetic diseases like neuronopathic MPS and I am grateful to be in a position (in industry) to help on a global level. It is the reason why I left my clinic and joined Ultragenyx - to have a greater impact in bringing forward new therapies to treat the brain and ultimately to be able to reach more patients and families. However, we are seeing a lack of progress in these promising programs. It has been heartbreaking to see viable therapies discontinued. The Reagan Udall Biomarker Workshop on CSF HS in nMPS that occurred last Wednesday, February 21 was a pivotal moment in the rare disease space because it demonstrated that there is a consensus from the medical/scientific, industry and patient/caregiver community about the path forward for drug development in nMPS. There is overwhelming evidence that CSF HS is a reasonably likely surrogate endpoint to predict clinical outcomes and therefore appropriate for use in an accelerated approval pathway. I was honored to be involved in coordinating this workshop and to present alongside my physician colleagues, renowned scientists in MPS, and most importantly, the parents of children affected by this group of devasting diseases. We provided a unified and loud message that the time is NOW to act swiftly. We cannot wait any longer as another generation of children die while awaiting access to life saving therapies. #Timeisbrain. https://lnkd.in/exssNXHp
Qualifying Biomarkers to Support Rare Disease Regulatory Pathways
reaganudall.org
To view or add a comment, sign in
-
Too old for paediatric trials, too young for adult trials Participants between 13 and 24 were included in only 0.04% of paediatric/adult oncology clinical trials where the minimum age for eligibility was 13. - https://lnkd.in/dsZzq-hq #clinicaltrials
Too old for paediatric trials, too young for adult trials
clinicaltrialsarena.com
To view or add a comment, sign in
-
A patient finished treatment today and we had our bell-ringing ceremony for him. We are a tiny department and 6-7 of us are usually there. The patient typically says a few words, we share some laughs and tears with them and wish them luck. "Simul, are you ignoring the evidence that says this is potentially harmful? There may be unintended consequences." There are actual studies on this - about the "harms" of ringing the bell. Life is not simple and cannot always be simulated with a randomized trial. A few times a week, in the midst of the routine of work, the sadness of loss, we celebrate our patients. We ask them if they would like to ring the bell at the end of treatment. A minority of patients say "nah, I'm good" and we respect that. But, most say yes. Why do I do this in spite of "the evidence"? Note, I am saying evidence with many many grains of the most sarcastic salt you will find. - We are rarely all together in the department with the patient, as we all have our own roles. But, here we get to spend this moment with the patient and their family. - The patient just did something really hard! If they choose to celebrate it, we are here for them. If not, we will see you in 2 weeks. - It is a safe space for tears - there are times when every single one of us and the patient and family emote. It's okay even for you doctor to share a cry with you. - Patients that are really into it bring their family - kids, friends, partners. We get to celebrate with them, as well, and to see the people that will help take care of our patient when we aren't in the picture. Overall, the patients that choose it very much appreciate it. This is seen over the course of years and being a perceptive reader of people. There is a "killjoy" nature in oncology that want to take away even the smallest of joys. We are a community clinic in the truest sense of the word - we provide care, but also sometimes money for groceries and rent and prayers and rides. My door is literally always open and patients walk in on random days to chat. When you read studies like this or that resident Steve that says things like "Actually, ringing the bell might be harmful" (Steve is so annoying!), think a little more deeply about this. If you're at some center where you flew in, saw a student, a resident, a fellow and occasionally an attending physician once in a while, then flew out, this ceremony may not be appealing. If you are being taken care of by your neighbors and friends, people you attend church with or play pickleball with, people that you'll see out in the world that feel connected to you, celebrating small victories may be one of the small joys that keep patients going. And stop wasting time and energy studying this stuff. Just learn how to be a person. https://lnkd.in/gcFTMXvc.
Ringing a Bell on the Last Day of Radiation Therapy: Helpful or Harmful?
ascopost.com
To view or add a comment, sign in
-
🚀 Exciting Update from Maggie's Pearl! 🚀 🔬 Trial Transitioned to Open Label: We're excited to see that the Phase III trial of oral epalrestat therapy in pediatric subjects with PMM2-CDG has now been green-lighted to transition to open label. Transitioning to open label means that participants who were previously receiving placebo now have the opportunity to receive the active treatment openly, providing direct observation of its effects and allowing for a more comprehensive assessment of its efficacy. 🌟A Journey from C. elegans Screening to Clinical Trial: Starting with screening compounds in C. elegans, researchers and stakeholders identified epalrestat as a potential candidate for further investigation. Through collaboration and innovation, the journey from laboratory discovery to the initiation of a Phase III clinical trial has brought hope to PMM2-CDG families worldwide. As fellow contributors to the field of C. elegans drug discovery, we applaud the efforts of all involved. Together, we're making strides towards improving the lives of individuals affected by diseases, as well as keep people healthier for longer. To read the details visit: https://lnkd.in/d_KCfy39 #RareDiseaseResearch #PMM2CDG #Epalrestat #ClinicalTrial #MaggiesPearl #MayoClinic #ResearchBreakthrough #celegans
Phase III clinical trial of pediatric subjects with PMM2-CDG begins crossover to open label epalrestat
prnewswire.com
To view or add a comment, sign in
-
If you’re an oncology nurse, having a questioning attitude is one of the most valuable safety tools you possess. Learning and teaching patients about availability of genomic testing and the implications of preventing serious and sometimes life threatening toxicities from chemo can mean safer more precise choices and dosage. The experience of cancer treatment is as individual as the person. We are the gatekeepers and safety nets for our patients. This is a terrific review of pharmacodynamics that takes about 40 minutes to get us thinking more deeply about the future of cancer care and precision medicine.
As the primary point of contact for patients with cancer, oncology nurses are in a key position to educate and guide patients and caregivers regarding these treatments, and to help to ensure equitable access to them for all patients. Gain valuable insights into pharmacogenomics, a subset of precision medicine and its implications in cancer care with this webinar: https://bit.ly/3H4Qers
Pharmacogenomics: Clinical and Advocacy Implications for Oncology Nurses
https://vimeo.com/
To view or add a comment, sign in
-
HOT OFF THE PRESS! Pediatric #rarediseases - those that primarily impact children, and often take their lives before they have a chance to experience adulthood - are particularly hard to study, and #drugdevelopment for these therapies is particularly risky. That is why #Congress established the rare pediatric disease (RPD) priority review voucher (PRV) program in 2012 to create additional incentives to study these diseases. The success has been resounding. To date, many rare disease communities have directly benefitted from drug development made economically possible by the program, and many children and families had the chance to live longer, fuller lives as a result. As many as 35 different rare disease communities have received vouchers. Yet, one key piece of information missing about the program so far has been how the program shapes the earlier pipeline of new therapies - after all, it takes many years to develop a rare disease drug and RPD designations, different from orphan drug designations or RPD vouchers, are not publicly announced. Fortuitously, FDA just published data on these designations for the first 10 years of the program, confirming the immense benefit of this program for the rare disease community! Authorization for the RPD PRV program is set to expire on September 30th of this year. Last week, the Creating Hope Reauthorization Act, legislation to reauthorize the program, was introduced in the House with strong bipartisan support. The new data just released makes it clear that the program fosters rare disease drug development and that Congress should reauthorize the program asap - too many lives depend on it!
Analysis of the first ten years of FDA’s rare pediatric disease priority review voucher program: designations, diseases, and drug development - Orphanet Journal of Rare Diseases
link.springer.com
To view or add a comment, sign in
-
'Radiopharmaceuticals offer a survival benefit to mCRPC patients as well as managing bone pain and #QoL' One of the key clinical takeaways of our latest GU NURSES CONNECT #OncologyNursing update. Get the rest & watch the 3-min video: https://ow.ly/ngbj50PNKUY #MedEd #PCSM
Nursing Support for mCRPC Patients During Radiopharmaceutical Treatment | COR2ED
https://cor2ed.com
To view or add a comment, sign in
-
The Council of Ministers approved an amendment to the Royal Decree on paediatric oncology in Belgium which groups patients in a smaller number of reference centres and creates networks to organise parts of the treatment trajectory close to the patient's home. This measure follows the recommendation of the European Reference Network for paediatric oncology (ERN PaedCan), which says that reference centres should treat at least 100 new cases per year, instead of the current minimum of 50. Doctors and other caregivers now face the challenge of organising such networks between reference centres and shared proximity care with the aim to provide the best chance of survival for each child while ensuring quality of life and survival during treatment and beyond. Read more here: https://lnkd.in/eckzFjzF
Royal Decree on paediatric oncology in Belgium
bspho.be
To view or add a comment, sign in