We are proud to announce our newest test, the KNOVA Prenatal Cell-Free DNA Screen (NIPT/NIPS). Fulgent’s KNOVA Prenatal Cell-Free DNA Screen is a novel approach to non-invasive prenatal testing/screening (NIPT/NIPS). Its stand-out feature is the ability to analyze more targets than standard prenatal tests, covering chromosomal aneuploidies, chromosomal microdeletions, and 𝘥𝘦 𝘯𝘰𝘷𝘰 SNVs in 50 genes. With just a simple maternal blood draw as early as 10 weeks into a pregnancy, KNOVA Prenatal Cell-Free DNA Screening can help identify pregnancies at risk for severe, early-onset disorders and guide decision-making. Learn more at https://lnkd.in/gtj5pcqp.
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Join us next Wednesday, February 14 at #SMFM24 for a panel discussion and live Q&A! Maternal health matters: findings from prenatal genetic screening with applications beyond pregnancy care Wednesday February 14th 7:30am - 8:30am ET Chesapeake D This presentation will review recently published studies where prenatal cell-free DNA (#cfDNA) screening and reproductive carrier screening results reveal information relevant to maternal health, including 🧬 SNP-based prenatal cell-free DNA screening results suspicious for maternal malignancy 🤰 Carrier screening results with potential for carrier manifestations during pregnancy 📊 Non-reportable NIPT results indicate increased risk for pregnancy complications #Natera
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The effectiveness and safety of intrauterine infusion of autologous regulatory T cells (Tregs) in patients with recurrent pregnancy loss and low levels of endometrial FoxP3 cells: A retrospective cohort study https://lnkd.in/gQmVRm4m
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Ensure maternal and infant health by screening pregnant women for syphilis, a vital step in prenatal care. 👩⚕️🤰 The Ob-Gyn Group advises screening pregnant women for syphilis, emphasizing the importance of early detection and treatment to prevent adverse outcomes for both mother and baby. Syphilis, a sexually transmitted infection, can lead to serious complications if left untreated during pregnancy, including stillbirth, preterm birth, and congenital syphilis in newborns. By implementing routine screening protocols, healthcare providers can identify and treat syphilis in pregnant women, reducing the risk of transmission to the fetus and improving maternal and infant health outcomes. This recommendation underscores the critical role of prenatal care in safeguarding the well-being of expectant mothers and their babies. . . . . . . Read full article: https://lnkd.in/dHYGhqP3 #PrenatalCare #SyphilisScreening #MaternalHealth
Screen Pregnant Women for Syphilis, Ob-Gyn Group Advises - Providing you the fresh information
https://www.entertainmentrush.com
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Anaemia This is defined as a reduction in the haemoglobin concentration of the blood below normal for age and sex. Although normal values can vary between laboratories, typical values would be less than 135 g/L in adult males and less than 115 g/L in adult females. From the age of 2 years to puberty, less than 110 g/L indicates anaemia. As newborn infants have a high haemoglobin level, 140 g/L is taken as the lower limit at birth. Alterations in total circulating plasma volume as well as of total circulating haemoglobin mass determine the haemoglobin concentration. Reduction in plasma volume (as in dehydration) may mask anaemia or even cause (apparent, pseudo) polycythaemia, conversely, an increase in plasma volume (as with splenomegaly or pregnancy) may cause anaemia even with a normal total circulating red cell and haemoglobin mass. After acute major blood loss, anaemia is not immediately apparent because the total blood volume is reduced. It takes up to a day for the plasma volume to be replaced and so for the degree of anaemia to become apparent.Regeneration of red cells and haemoglobin mass takes substantially longer. The initial clinical features of major blood loss are therefore a result of reduction in blood volume rather than of anaemia. Copied : Hoffbrand’s Essential Haematology
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🤰 Current study on pregnancy sheds light on the challenges in diagnosing pregnancy-related diseases, including #preeclampsia Asif Ahmed PhD FRSB The scoping review examined 152 studies investigating extracellular vesicles (EVs) in pregnant women's blood. Findings suggest increased EV concentrations during pregnancy and in certain pathologies. Standardizing methodology and exploring EV functionality are key for unlocking their diagnostic potential. Exciting prospects for gestational disease research! #PregnancyResearch #EVs
Circulating extracellular vesicles in healthy and pathological pregnancies: A scoping review of methodology, rigour and results
onlinelibrary.wiley.com
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Macrophage plasticity and function in cancer and pregnancy https://lnkd.in/g5UdJVS4
Macrophage plasticity and function in cancer and pregnancy
frontiersin.org
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soluble Fms‐like tyrosine kinase‐1 (sFlt-1)/placental growth factor (PlGF) ratio, biomarkers of placental function and adverse pregnancy outcomes. Study of 158 RA pts, 1/2 on TNFi during Preg. TNFi assoc w/ incr birthweight; no effx on sFlt‐1 & PlGF
https://www.ahajournals.org/doi/full/10.1161/JAHA.123.032655
ahajournals.org
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Cancer and pregnancy are prothrombotic states that increase risk of venous thromboembolism. But what is the risk when both cancer and pregnancy present in the postpartum period? In this analysis of 10 428 pregnancies with cancer, enous thromboembolism incidence in individuals with cancer at 42 and 330 days was 1.11% and 2.19%. Further study is needed to identify optimal VTE prophylactic strategies for this population! https://lnkd.in/gxxzcfYG Jennifer Cate Alex Sundermann Alexa Campbell Ronan Sugrue Sarah Dotters-Katz Andra James Evan Myers Jerome (Jeff) Federspiel
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