EntityRisk’s Post

Are you catching today’s 1:45pm session at ISPOR - “I Have a Better QALY Than You: How to Make Sense of Alternatives to the QALY for Research and Policymaking"? Tell us how you think the debate went, we want to hear your thoughts. #HEOR #ISPOR #DrugPricing #BioPharma #ISPOR24

I Have a Better QALY Than You: How to Make Sense of Alternatives to the QALY for Research and Policymaking This promises to be compelling debate at ISPOR with Dan Ollendorf moderating. Our co-founder and chief scientific officer Darius Lakdawalla will be joined by Melanie Whittington and Anirban Basu. Learn more about the panel here: https://lnkd.in/gSAA-HZA #HEOR #ISPOR #DrugPricing #BioPharma #ISPOR24

The CHMP Grants Positive Opinion to Roche’s Vabysmo for Retinal Vein Occlusion (RVO) #roche #vabysmo #faricimab #retinalveinocclusion #regulatory #chmp #positiveopinion #phase3 #balaton #comino #aflibercept #macularedema #visualimpairment

Join Anna Krause during Venom Week 2024, which starts on June 5th in Durham. Anna will present the results of Phase I clinical study of Marimastat, a potent inhibitor of snake venom metalloproteinases (SVMPs) Marimastat showed excellent efficacy in in vivo models of snakebite envenoming, protecting mice from lethal doses of various venoms of viperid snakes. It has the potential to become a safe, efficient, and affordable oral drug for snakebites, protecting victims against tissue damage and hemorrhage and, ultimately, from limb amputation or even death. To the best of our knowledge, Pikralida is the only company in the world with a current regulatory dossier, GMP-quality Marimastat, and a drug product suitable for human use. Learn more about the event: https://venomweek.com/ #WHO #VenomWeek2024 #snakebites #drugdevelopment #marimastat #Pikralida

Another day another piece of oligo news... This time from Tiba Biotech, who received a BARDA contract to leverage its non-LNP delivery technology for an RNAi-based treatment for swine flu. We wrote about the limitations of LNPs extensively over the years. They saved the day during the pandemic, but also stunted critical R&D on better, novel delivery technologies. LNPs are blunt instrument with lots of potential toxicity concerns. A better delivery vehicle would dramatically enhance the field of precision medicine and nucleic acid therapeutics. I suspect as the pandemic is further in the rear-view, we'll begin seeing more public work around novel delivery vehicles. What do you think about LNPs? We've called them "lamentable nano payloads" in the past. Do you agree? https://lnkd.in/g-csFF_f #oligo #RNA #drugdevelopment #pharma

Camurus Presents Results from the P-III (ACROINNOVA 2) Study of Octreotide SC Depot (CAM2029) to Treat Acromegaly #camurus #octreotide #cam2029 #acromegaly #clinicaltrial #phase3 #somatostatinligands

#Nomeculature_series #Autonomic_Nervous_System Let's make memorizing drug names easier! #Pancuronium Pan: is a prefix indicating the multiple functional groups in a compound. Onium: refers to the two quaternary ammonium groups. Join me and Atheer Alrawashdeh on our enlightening adventure as we explore the world of #drugnaming #pharmacology.

Catch a concise 15 min update (or three) on key topics for the Pharamceutical Industry #methodmodernisation #nitrosamines #oligonucleotide analysis Link below ! #waters

Analyze Thermal Melt Faster. A Best practice guide to optimize your thermal melt experiments for both time and accuracy. An interesting calculator on thermal melt experiments!!