Dynamic42 GmbH’s Post

We are excited to announce 📣 the launch of our new DynamicOrgan System!   The open organ-on-chip platform   You can now build human in vitro disease and infection models with the DynamicOrgan System. A system that includes pumps, biochips, consumables, and the freedom to keep using standard laboratory equipment.   / No capex spending / No need for specialized equipment / Work with equipment you already have / Works with established standards / Easy access to training / Scalable sample number & tissue complexity   Learn more here: https://lnkd.in/gVFF3UiW     #DynamicOrgan #organonchip

Sometimes, although we know which technology we want to implement in our research, it is difficult to take the leap and actually go for it. We get it… it’s an investment, it takes time to learn a new method, time most of us don’t have, there is always the uncertainty if it will deliver the results that you need and work as promised. So here are a few things that we do to lower the burden: 1. We offer in depth technology courses that enable you to test the method with your own hands even before you purchase the system. 2. We always do 1-on-1 calls with you and our R&D scientists to discuss your specific project to really assess your possibilities. 3. We offer a system that requires no capital investment and enables you to keep using existing equipment. here is a generalized workflow of our method to give you a first idea on what to expect when you use the #DynamicOrgan System in your lab.

Imagine for a moment a human in vitro model that is: / multicellular / includes vascularization / microbiome / pathogens (if needed) / is immunocompetent / and easy to use Wakey wakey 😴 zzz…your dream has come true! Our #DynamicOrgan System will help you get greater and more meaningful insights into human biology swiftly and without capital spending!

Thank you everyone for voting in our survey on "How can we accelerate the adoption of organ-on-chip technology?" Over 40% voted that we need greater regulatory acceptance, but almost a quarter of participants equally said that we need to reduce product cost and make OoC technology more accessible to a wider audience. With our #DynamicOrgan System we provide just that, no capex spending for proprietary equipment, low running cost, and you can work with equipment you already have in your lab.

In our recent survey, over 40% voted that we needed greater adoption of NAM's by regulatory bodies to accelerate their adoption.   The European Commission has now released their report on the EC workshop about “The Roadmap Towards Phasing Out Animal Testing for Chemical Safety Assessments” from December 2023.    Here, we have summarized our 12 most important takeaways from that document.   1. Validation Challenges and Requirements 2. Regulatory Acceptance of NAMs 3. Partnerships and Networks 4. Stakeholder Involvement 5. Socio-Technical Barriers 6. Education and Training 7. Funding and Cost of Validation 8. Case Studies and Practical Examples 9. Legislative and Guidance Updates 10. Non-Test Approaches and In Silico Models 11. Development of Quantitative Adverse Outcome Pathways (qAOPs) 12. Commitment to Phasing Out Animal Testing   You can find the full report here: https://lnkd.in/g8h96DUM

[𝐍𝐞𝐰 𝐛𝐥𝐨𝐠] Organ-on-chip applications by organ type – what has been done? This blog aims to be a resource for everyone wanting to screen for what has been done in their organ of interest to identify models that would fit their research questions. Read it here: https://zurl.co/ti8O

Scientists in biomedical research need human-relevant in vitro models. But what are the current roadblocks for scientists in academia to adopt respective technologies? Unfortunately, there is a limit to the options we can give in a survey, please comment if you can think of more roadblocks other than the ones mentioned.

And the winner is... Anaïs Hubart from the KU Leuven! 🎉 Congratulations, you were the only one to guess the right number of plugs in the 50ml centrifuge tube. Very soon, you will receive your very own #DynamicOrgan Developers Kit. For everyone else, we are very sorry you didn't win this time, but you will have a little gift waiting in your inbox nevertheless. If you are curious on what the right answer was or about the distribution of answers submitted, check the carousel below!

Our most recent article is now live in GIT Labor-Fachzeitschrift titled: "Organs-on-Chip: nachhaltige Alternative für die Wirkstoffforschung"