New Post: EPA Announces Public Meetings of the Science Advisory Board Inorganic Arsenic Review Panel - https://lnkd.in/eAatcXyG
Association of State Drinking Water Administrators (ASDWA)’s Post
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#CES Just published Synthesis and Characterization of Energetic Molecules Based on Pyrimidine Rings: selection and verification of computational-assisted synthesis pathways https://lnkd.in/deUwd4MY
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Organic and Medicinal Chemist | Drug Discovery | Chemistry | Executive Management | Cross-Functional Collaborator | Lead Optimization | Waterfall | R&D | Cricket | Vedic Astrology |
https://lnkd.in/ghSmya6s This research describes the challenges associated with nucleophilic fluorination of electron-deficient azaarenes, particularly due to the high energy of Wheland intermediates and the dominance of fluoride elimination over hydride elimination. However, a novel approach is introduced, involving a chain process with asynchronous concerted F–-e–-H transfer, which bypasses the formation of azaarene Meisenheimer intermediates. This innovative strategy enables the successful nucleophilic oxidative fluorination of quinolines, presenting a significant advancement in the field of C–H fluorination.
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Stereospecific Synthesis and Biological Evaluation of #KRN7000 Analogues with Thio-modifications at the Acyl Moiety. Biological activities of phenyl glycolipids with thio-modifications at the acyl moiety remain unknown, and facile approaches for highly stereoselective synthesis of KRN7000 and its analogues are rather scarce.
Stereospecific Synthesis and Biological Evaluation of KRN7000 Analogues with Thio-modifications at the Acyl Moiety
pubs.acs.org
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Current Issues in Molecular Biology is an international, scientific, peer-reviewed, open-access journal (ISSN: 1467-3045, IF 2.8) on molecular biology, published monthly online by MDPI.
📰‼️ In this paper, the authors investigated the "Bicarbonate-Independent #Sodium Conductance of Na/HCO3 Cotransporter #NBCn1 Decreases NMDA Receptor Function" 📣 Find out more about this study here: https://lnkd.in/eYUB3E7c
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Have a look at “Stereoisomeric Tris-BINOL-Menthol Bulky Monophosphites: Synthesis, Characterisation and Application in Rhodium-Catalysed Hydroformylation” 👉https://ow.ly/oijR50Q4ryC #mdpimolecules #molecules_mdpi
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https://lnkd.in/daq2a_k The Paal-Knorr Thiophene Synthesis - An short introduction and some recently published papers
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Poster presented at the 5h International Wroclaw Scientific Meetigns. Tittle: "Binding interaction of new N-Substituted 1H-Isoindole-1,3(2H)-Dione derivatives with ctDNA”. #5iwsm #poster #chemistry #binding interaction
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First and second order hyperpolarizabilities of flavonol derivatives: A density functional theory study August 2022Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 283:121728 DOI: https://lnkd.in/da7GAWwK
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Natural Product Scientist | NMR Specialist | Structural Characterization | Chiroptical Spectroscopy | Molecular Modeling | NMR-Anisotropy (RDC & RCSA)
Unlocking Molecular Mysteries: Residual Chemical Shift Anisotropy (RCSA) Revealed! Discover how RCSA-based enantiodifferentiation in chiral liquid crystals unveils the hidden secrets of molecular configurations. 🧪📊 #Chemistry #NMR #RCSA #Anisotropic-NMR https://lnkd.in/eJUzi99S
Residual‐Chemical‐Shift‐Anisotropy‐Based Enantiodifferentiation in Lyotropic Liquid Crystalline Phases Based on Helically Chiral Polyacetylenes
onlinelibrary.wiley.com
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I'm ecstatic to share that our manuscript titled, "Diastereoselective [3 2] Cycloaddition between Tertiary Amine N‑Oxides and Substituted Alkenes to Access 7‑Azanorbornanes" was recently accepted into Organic Letters! I'd like to thank all of the contributing authors for their hard work on this project! Brief Description: We developed an efficient synthesis to access 43 novel nitrogen-containing heterocycles using commercially available or readily accessible starting materials. The core structure (7-azanorbornane) has demonstrated relevance as non-opioid pain relievers, dopamine transporters, glycosidase inhibitors, and possible anti-malarial treatments. You can read the full article free of charge at: https://lnkd.in/eVehQ8YH
Diastereoselective [3 2] Cycloaddition between Tertiary Amine N-Oxides and Substituted Alkenes to Access 7-Azanorbornanes
pubs.acs.org
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