ARTBIO’s Post

🔬Automating protocols for capturing and immunolabelling breast cancer cells is easy with Fluigent’s Aria. The process involves: ✅Surface treatment ✅Injection of antibody-coated beads and cell suspension ✅Immunostaining protocols 👀 Check out this application note, made in collaboration with Emile Lakis, PhD, from Institut Curie's, Team MMBM (Macromolecules and Microsystems in Biology and Medicine), using an EPHESIA microfluidic chip. Adapt your protocol and make use of the Aria’s specific features to optimize your experiment! ⚙️ 👉Read application note here: https://bit.ly/3TgUz1U 👉Learn more about Aria here: https://bit.ly/4a3AK4l #Aria #Microfluidic #Antibody #InstitutCurie

The proteomics of tumors is such a hot topic these days! Register now to learn more!

This will be an interesting webinar! Register now below! 

🥇Check out the Editor's Choice #Article "Melanin and Melanin-Functionalized Nanoparticles as Promising Tools in Cancer Research—A Review" 👥by Iasmina Marcovici, Dorina Coricovac et al. Victor Babeş University of Medicine and Pharmacy, Timişoara 📝Link here: https://lnkd.in/dSbTB_4h ✨The review highlights the potential of melanin, a natural polymeric pigment, as a promising candidate for nanotechnology-based cancer treatment due to its unique physicochemical properties and innate antioxidant, photoprotective, anti-inflammatory, and antitumor effects✨

🔬 🌟 Update! ⏲ Timing shifted to 4:30 PM Join Prof. Herbert Levine's talk on "The Forever War Against Cancer" at ICTS, Ramanujan Lecture Hall. 📌 Register now or drop in for a groundbreaking discussion! https://bit.ly/sl_mar2024 #cancerresearch #ictstifr #bengaluruevents #ScientificTalk #Cancer #biophysics #biotechnology #medicalphysics

🌟 Excited to share the publication of our last research in Frontiers in Bioengineering and Biotechnology! 🌟 It's well-known how crucial the mechanics of cancer cells are, but what happens after traditional cancer treatments like radiotherapy? 💡🔬 Our latest study dives into this question, revealing fascinating insights into the effects of ionizing radiation on breast adenocarcinoma cells. Through our research, we've discovered how radiation and substrate stiffness impact cell mechanics, leading to changes in paxillin expression, cytoskeletal stiffness, and cytoplasmic/nuclear morphology. These findings open up new avenues for innovative therapeutic strategies and optimizing radiation therapy. 🚀✨ 📖🔗Curious to learn more? Check out the full article here: https://lnkd.in/df4X7E5S Rocco Mottareale Valeria Panzetta Cecilia Arrichiello Paolo Muto Paolo Netti Mariagabriella Pugliese

We are pleased to share the latest publication from our laboratory, a result of collaboration between #AssamUniversity and #SahaInstituteofNuclearPhysics. This study investigates the impact of C70 and C60 fullerenes on quinazolinone, specifically in quinazolinone–fulleropyrrolidine nanohybrids. The nanohybrids Q3C70M and Q3C60M exhibit distinct spectral shifts and have significant photobiological antineoplastic properties. Q3C60M enhances apoptosis, while Q3C70M reduces Cyclin A levels and counteracts oncogenic effects by promoting cell differentiation. Q3C70M demonstrates heightened cytotoxicity by overcoming chemotherapy resistance by modulating BAX and BCL-2 levels. This innovative approach, distinguishing between C70 and C60, represents a novel contribution to the existing scientific literature. https://lnkd.in/dBbb9dNx #science #research #cancer #organicchemistry #organicsynthesis #medicinalchemistry #cancerphotodynamictherapy #ACS #ACSMedicinalChemistryLetters #AssamUniversity #SahaInstituteofNuclearPhysics

It is exciting to witness how bioprinting continues to be an integral tool in cancer research. 🧑🔬👩🔬In a recent study, researchers from the University of California, Los Angeles developed an innovative approach for organoid screening. This method combines bioprinting with high-speed live cell interferometry (HSLCI), a non-invasive and label-free imaging technique that captures time-resolved images of living cells. 🔬By leveraging the BIO X bioprinter, the research team achieved high precision and consistency in controlling the printed constructs' temperature, shape, and size. This level of control greatly facilitated downstream analysis. 🤖Additionally, incorporating machine learning strategies significantly improved image segmentation and track filtering, leading to a substantial increase in the number of organoids that can be effectively tracked. This integrative method addresses previous challenges and paves the way for possible future clinical applications in cancer treatment. Read the full study here: https://ow.ly/Vsnf50PAHnn #bioprinting #organoids #livecellimaging #cancerresearch #analysis #tissueengineering

Are you a researcher involved in PET tracer development, cancer biology and therapeutics, or a nuclear #imaging specialist? Tune in for the free webinar "Hypoxia in the Tumor Immune Microenvironment (TIME)" on July 11, at 4 PM CEST: https://lnkd.in/diPbuZYc Prof. Zaver M. Bhujwalla, at Johns Hopkins Medicine, will review in vivo (e.g. PET/MR) and cellular and molecular (e.g. MRI/NMR spectroscopy) preclinical studies that provide new insights into varied tumor profiles/types and the underlying interplay in PD-L1 status, hypoxia, and fibroblasts in the tumor microenvironment. Such insights pave the way for improved therapies. #NMR #MRI #PreclinicalImaging #Hypoxia #Oncology

The role of immunosuppressive cells in tumor progression significantly influences treatment efficacy and cancer prognosis. Accurate visualisation and real-time evaluation of these cells are crucial for precision oncological medicine. In this this review Bao G, Zhou J, Cheng S, et al from Huazhong University of Science and Technology highlight the importance of noninvasive imaging techniques, discussing recent advancements in molecular imaging probes designed to monitor protumoral immunosuppressive cells within the tumor microenvironment. Read more 👉 https://lnkd.in/efn4E3zW #Immunosuppression #CancerResearch #PrecisionMedicine