Eric Kelsic
Cambridge, Massachusetts, United States
2K followers
500 connections
About
Dyno is pioneering use of artificial intelligence and machine learning for improving gene…
Activity
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I'm honored to step into this role and look forward to working alongside the incredible #teamSpark to unlock the transformative power of gene…
I'm honored to step into this role and look forward to working alongside the incredible #teamSpark to unlock the transformative power of gene…
Liked by Eric Kelsic
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Generative science will be labeled humanity’s greatest invention because it will be an invention that can invent. I spoke with three of the top minds…
Generative science will be labeled humanity’s greatest invention because it will be an invention that can invent. I spoke with three of the top minds…
Liked by Eric Kelsic
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A few days ago, our Roche leadership team had the exciting opportunity to meet with NVIDIA at their headquarters in Santa Clara. Bringing science…
A few days ago, our Roche leadership team had the exciting opportunity to meet with NVIDIA at their headquarters in Santa Clara. Bringing science…
Liked by Eric Kelsic
Experience
Education
Publications
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RNA Structural Determinants of Optimal Codons Revealed by MAGE-Seq
Cell Systems
We developed a new technique called MAGE-seq to enable rapid and quantitative phenotyping of mutant libraries in E. coli, and apply it to understanding codon preferences in an essential translation initiation factor gene. We find that 5′ RNA structure determines codon preferences even far from the start codon and that synonymous codons that disrupt the native 5′ RNA structure are more deleterious.
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Spatiotemporal microbial evolution on antibiotic landscapes
Science
We visualized evolution by recording timelapse videos of bacteria growing on a MEGA-plate (a giant agar dish) and evolving to 1000x antibiotic resistance levels over a 3 week period. We then use DNA sequencing and lineage tracing to study the mutations that confer resistance. https://www.youtube.com/watch?v=plVk4NVIUh8
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High-order species interactions shape ecosystem diversity
Nature Communications
We show that high-order species interactions can counter-intuitively create a lower bound on ecosystem diversity.
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Counteraction of antibiotic production and degradation stabilizes microbial communities
Nature
Guided by experimental insights, we propose a new mechanism for maintaining diversity in microbial communities that contain antibiotic producing and degrading species.
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Comparing community structure to characteristics in online collegiate social networks
SIAM Review
We study the structure of early Facebook collegiate social networks using community finding algorithms.
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Honors & Awards
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National Defense Science and Engineering Graduate (NDSEG) Fellowship
Office of Naval Research
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High School Valedictorian
Longmont High School
Languages
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English
Native or bilingual proficiency
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Chinese
Elementary proficiency
More activity by Eric
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Come join us at Dyno Therapeutics! 🚀 🌟 I am hiring a Sr. Manager/Manager - Laboratory Operations🌟 In this role you will be responsible for…
Come join us at Dyno Therapeutics! 🚀 🌟 I am hiring a Sr. Manager/Manager - Laboratory Operations🌟 In this role you will be responsible for…
Liked by Eric Kelsic
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Looking forward to speaking at the 4th Next Generation Gene Therapy Vectors Summit (June 12-14, Boston), focused on innovating gene therapy capsid…
Looking forward to speaking at the 4th Next Generation Gene Therapy Vectors Summit (June 12-14, Boston), focused on innovating gene therapy capsid…
Shared by Eric Kelsic
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A spotlight of the The Washington Post on the evolving field of optogenetic restoration of sight. Almost 20 years in the making and building on the…
A spotlight of the The Washington Post on the evolving field of optogenetic restoration of sight. Almost 20 years in the making and building on the…
Liked by Eric Kelsic
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Dyno is gearing up for the annual conference of the American Society of Gene & Cell Therapy! At #ASGCT2024 we’ll be presenting three abstracts and…
Dyno is gearing up for the annual conference of the American Society of Gene & Cell Therapy! At #ASGCT2024 we’ll be presenting three abstracts and…
Liked by Eric Kelsic
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It’s a busy conference season here at Dyno! From May 8-9 we will be at #SynBioBeta2024 to share our recent successes applying AI to design better…
It’s a busy conference season here at Dyno! From May 8-9 we will be at #SynBioBeta2024 to share our recent successes applying AI to design better…
Liked by Eric Kelsic
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What does it mean to journey together? 🚀 For us at Dyno, it’s about coming together from across departments and across the country with a shared…
What does it mean to journey together? 🚀 For us at Dyno, it’s about coming together from across departments and across the country with a shared…
Liked by Eric Kelsic
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We remember David Goodstein, who died on April 10 at age 85. He served as a professor of physics and applied physics at Caltech for more than four…
We remember David Goodstein, who died on April 10 at age 85. He served as a professor of physics and applied physics at Caltech for more than four…
Liked by Eric Kelsic
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Normally, in the United States, when a 20,000 person arena is sold out, it's for a sports game or a concert. But #GTC2024, Jensen Huang reminded the…
Normally, in the United States, when a 20,000 person arena is sold out, it's for a sports game or a concert. But #GTC2024, Jensen Huang reminded the…
Liked by Eric Kelsic
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On #RareDiseaseDay, Terence R. Flotte, MD, told members of Congress that costs and logistics associated with product development remain barriers to…
On #RareDiseaseDay, Terence R. Flotte, MD, told members of Congress that costs and logistics associated with product development remain barriers to…
Liked by Eric Kelsic
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Today, we proudly recognize and honor the incredible women at Dyno Therapeutics who contribute their brilliance, passion, and dedication to driving…
Today, we proudly recognize and honor the incredible women at Dyno Therapeutics who contribute their brilliance, passion, and dedication to driving…
Liked by Eric Kelsic
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Thanks Elliot Hershberg for sharing the story of how Dyno Therapeutics got started and what we aim to achieve for our partners and for gene therapy…
Thanks Elliot Hershberg for sharing the story of how Dyno Therapeutics got started and what we aim to achieve for our partners and for gene therapy…
Shared by Eric Kelsic
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2023 has been an incredible year here at Dyno! Through the hard work and dedication of our team of AAViators, we were able to launch two new capsids:…
2023 has been an incredible year here at Dyno! Through the hard work and dedication of our team of AAViators, we were able to launch two new capsids:…
Liked by Eric Kelsic
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In a historic move today, FDA approved two cell-based #genetherapies, #Casgevy and #Lyfgenia, to treat #sicklecelldisease (#SCD) in patients 12…
In a historic move today, FDA approved two cell-based #genetherapies, #Casgevy and #Lyfgenia, to treat #sicklecelldisease (#SCD) in patients 12…
Liked by Eric Kelsic
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