Eric T. Williams, Ph.D.
Austin, Texas Metropolitan Area
770 followers
500 connections
About
Specialties: ADME, Toxicology, drug metabolism, cytochrome P450, carboxylesterase, in…
Experience
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Education
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The University of Texas Health Science Center at Houston (UTHealth)
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Activities and Societies: Community Outreach; West University Baptist Church
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Activities and Societies: National Residence Hall Honorary (NRHH), Residence Hall Association (RHA), Pre-Medical Society, Aggie Players, Grace Bible Church, First Baptist Church of College Station, Baptist Student Ministries
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Publications
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Discovery of a brain-sparing GIRK1/4 inhibitor for pharmacological cardioversion of atrial fibrillation
Bioorganic & Medicinal Chemistry Letters
Peukert S, Gulgeze Efthymiou HB, Mo R, Peng Y, Ma F, Barbe G, Bebernitz G, Fridrich C, Buono C, Williams ET, Daniels T, Li L, Zhang X, Adachi Y, Abe M, Taggart AKP
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Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin’s Lymphomas and Diffuse Large B-cell Lymphoma
Cancer Research Communications
Hamlin PA, Musteata V, Park SI, Burnett C, Dabovic K, Strack T, Williams ET, Anand BS, Higgins JP, Persky DO
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Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury
Cell Chemical Biology
Larraufie M-H, Gao X, Xia X, Devine PJ, Kallen J, Liu D, Michaud G, Harsch A, Savage N, Ding J, Tan K, Mihalic M, Roggo S, Canham SM, Bushell SM, Krastel P, Gao J, Izaac A, Altinoglu E, Lustenberger P, Salcius M, Harbinski F, Williams ET, Zeng L, Loureiro J, Cong F, Fryer CJ, Klickstein L, Tallarico JA, Jain RK, Rothman DM, Wang S
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A Phase I Dose Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies
Clinical Cancer Research
Hegde A, Jayaprakash P, Piha-Paul S, Karp D, Rodon J, Pant S, Fu S, Dumbrava EI, Yap T, Subbiah V, Couillault C, Bhosale P, Coarfa C, Higgins JP, Williams ET, Wilson T, Lim J, Meric-Bernstam F, Sumner E, Zain H, Nguyen D, Nguyen L, Rajapakshe K, Curran M, Hong D
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Have Stole, Will Travel: A Tribute to Henry W. Strobel, Jr.
The Pharmacologist
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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
Nature Chemical Biology
Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ
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Reversible Inhibition of Human Carboxylesterases by Acyl Glucuronides
Drug Metabolism and Disposition
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Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
Drug Metabolism and Disposition
Williams ET, Bacon JA, Bender DM, Lowinger JJ, Guo WK, Ehsani ME, Wang X, Wang H, Qian YW, Ruterbories KJ, Wrighton SA, Perkins EJ
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Investigation of the Metabolism of Rufinamide and Its Interaction With Valproate
Drug Metabolism Letters
Williams ET, Carlson JE, Lai WG, Wong YN, Yoshimura T, Critchley DJ, Narurkar M
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Characterization of Recombinant Human Carboxylesterases: Fluorescein Diacetate as a Probe Substrate for Human Carboxylesterase 2
Drug Metabolism and Disposition
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In Vitro Screening of Metabolic Clearance Using Two Concentration Points
Drug Metabolism Letters
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Genomic analysis of the carboxylesterases: Identification and classification of novel forms
Molecular Phylogenetics and Evolution
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The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
Drug Metabolism and Disposition
Williams ET, Jones KO, Ponsler GD, Lowery SM, Perkins EJ, Wrighton SA, Ruterbories KJ, Kazui M, Farid NA
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Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases
Journal of Pharmacological and Toxicological Methods
Williams ET, Ehsani ME, Wang X, Wang H, Qian YW, Wrighton SA, Perkins EJ
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The chimpanzee cytochrome P450 3A subfamily: Is our closest related species really that similar?
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics
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NAMD-LP: filtering and translating NAMD-generated files
Molecular Simulation
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Estrogen Regulation of the Cytochrome P450 3A Subfamily in Humans
Journal of Pharmacology and Experimental Therapeutics
Williams ET, Leyk M, Wrighton SA, Davies PJ, Loose DS, Shipley GL, Strobel HW
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Defining relationships between the known members of the cytochrome P450 3A subfamily, including five putative chimpanzee members
Molecular Phylogenetics and Evolution
See publicationWilliams ET, Rodin AS, Strobel HW
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