Spear Bio

Ultra-sensitive SPEAR technology surpasses conventional proximity extension assays with its two-factor authentication and streamlined workflow, delivering unmatched sensitivity and specificity. Detect blood-based proteins at sub-fg/mL levels in less than 1 µL of sample, with #qPCR readout. Please stop by Booth 740 at #AAIC24 in Philadelphia to learn about the work we’re doing with NfL and pTau 217! Not attending? Stay tuned for upcoming announcements about Spear Bio's UltraDetect™ assay kits and the launch of our new website! Learn More: https://lnkd.in/eEtP4X4A

Between March 2021 and February 2022, a study in Switzerland investigated the dynamics of SARS-CoV-2 neutralizing antibodies in 903 healthcare workers. The study results strongly supported that triple vaccination or natural infection following double vaccination results in a robust neutralization response, supporting booster doses. While additional boosters within three to six months after a third immunization event may not greatly enhance immunity, monitoring antibody decline beyond this window is crucial on an individual basis, considering new variants. The effectiveness of prior neutralizing antibodies against emerging variants is uncertain, highlighted by reduced immunity to recent Omicron variants. Incorporating newly appearing variants into booster vaccines could help address the challenge of sustaining effective long-term immunity. The FDA recently mandated XBB.1.5-specific COVID-19 vaccines for the upcoming season. NAB-Sure offers an XBB.1.5 specific assay and will be an effective and practical tool for assessing populations’ immune status and XBB.1.5 vaccine efficacy. To read on our website: https://lnkd.in/eKKETcGK Learn more about NAB-Sure: https://spear.bio/nabsure/ #Spearbio #Neutralizingantibodies #nabsure #SARSCoV2 #Omicron

We are happy to announce Spear Bio's ISO certification by BSI Group for "Quality Management System aligned with ISO 13485:2016."   This ISO 13485 certification is a recognition of our efforts to maintain the highest quality products and services for our customers.   Read more at: https://lnkd.in/eqTX4YwG   #ISO13485 #QualityMatters #NABSure #SpearBio

We’re #hiring a new Senior Scientist in Woburn, Massachusetts.

Dried Blood Spot (DBS) sampling is a powerful tool for SARS-CoV-2 serosurveillance. However, eluted samples from DBS typically have lower concentrations of neutralizing antibodies, which makes their measurement challenging.   Using an ultrasensitive immunoassay platform, NAB-Sure addresses these challenges. It exceeds the sensitivity of cell-based methods with the precision of an automatable cell-free assay. We showcase the sensitivity of NAB-Sure against other assays and validate NAB-Sure DBS result accuracy by comparing it with standard techniques in this app note.   Read more details on the application note here: https://spear.bio/3841-2/   #SpearBio #NeutralizingAntibodies #NABSure #COVID19Testing #VaccineEfficacy #FDA #SpearBio