RenBio is happy to announce the publication of a recent article in Pharmaceutics, “Enhancing In Vivo Electroporation Efficiency Through Hyaluronidase: Insights into Plasmid Distribution and Optimization Strategies." Led by Senior Research Engineer, Debnath Maji, we take a look into the promising realm of non-viral plasmid DNA delivery through intramuscular electroporation (EP) and highlight the role of hyaluronidase in enhancing transfection efficiency. Hyaluronidase has the ability to promote uniform distribution of plasmid DNA within skeletal muscle, and by leveraging bioimpedance measurements, we decipher changes induced by hyaluronidase treatment, allowing for further optimization of EP electrical parameters. This work underscores hyaluronidase's potential in augmenting in vivo EP efficacy and offers a roadmap for tailored EP strategies. Read the full article here, https://lnkd.in/ezUETurk!
RenBio
Biotechnology Research
Long Island City, New York 1,333 followers
DNA Therapeutics: Delivering Next-Generation Medicines
About us
RenBio was founded on the principle that the remarkable medical benefits of antibody therapeutics should be available to everyone, and was named one of DARPA’s “Biotech Startups of the Future” one year after opening its operations. The company was co-founded by David D. Ho, MD (Time magazine's "Man of the Year" in 1996 and recipient of the Presidential Citizens Medal) and Yaoxing Huang, PhD, visionary scientists affiliated with the Aaron Diamond AIDS Research Center and Professors at Columbia University Medical Center. RenBio is backed by the Bill & Melinda Gates Foundation, DARPA, and a syndicate of private investors, and is headquartered at the Alexandria Center® for Life Science in New York City.
- Website
-
http://www.renbio.com
External link for RenBio
- Industry
- Biotechnology Research
- Company size
- 11-50 employees
- Headquarters
- Long Island City, New York
- Type
- Privately Held
- Specialties
- Biotechnology, Antibody Engineering, and Antibody Delivery
Locations
-
Primary
30-02 48th Ave
Suite, 340
Long Island City, New York 11101, US
Employees at RenBio
-
Andrew Cameron
Senior Research Engineer
-
Carleigh Sussman
Research Associate II at RenBio
-
Delcora Campbell, MS, STEM-MBA
MS Translational Medicine |Research Associate II | AP Bio Instructor | MBA | President, Healthcare Association Club (Gabelli School of Business)|…
-
Marek Drozdz
Director of Research at RenBio | Cancer Biology and Cell Signaling | Innovation
Updates
-
RenBio is seeking a Research Scientist I/II to join our team! Are you interested in cutting-edge technologies and want to change how we fight infectious diseases? If so, this position might be perfect for you. Apply now at https://lnkd.in/g_AG4KfK or share with your network!
Job description
scismic.com
-
Exciting Opportunity at RenBio! Join our innovative team as a Research Associate. We're looking for a highly motivated and goal-oriented individual to contribute to our dynamic and collaborative research environment. If you're passionate about pushing scientific boundaries, fostering innovation, and making a significant impact, we want to hear from you! Apply now at https://lnkd.in/epM_ZQQm or share with your network!
Job description
scismic.com
-
RenBio is thrilled to announce that our most recent review , "Delivery of DNA-Based Therapeutics for Treatment of Chronic Diseases,” is out (https://lnkd.in/e8usgcgs)! Led by Research Associate Carleigh Sussman, it provides a comprehensive overview of gene therapy's evolution and its pivotal role in modern medicine. It delves into the promise of DNA-based medicines, particularly in managing chronic conditions more effectively. The review explores two key DNA-based gene therapies: adeno-associated virus (AAV)-based gene therapy and plasmid DNA (pDNA)-based gene therapy. It discusses how both have shown immense potential in clinical trials, offering robust and durable expression of therapeutic genes with fewer treatments compared to traditional approaches. Moreover, this review sheds light on the use of electroporation (EP) as a method for pDNA delivery. EP has emerged as a promising technique to enhance the efficacy and durability of pDNA-based therapies, paving the way for more efficient treatment strategies for chronic diseases. #GeneTherapy #ChronicDiseases #ResearchInnovation
Delivery of DNA-Based Therapeutics for Treatment of Chronic Diseases
mdpi.com
-
Thrilled to announce that Dr. Rachel Liberatore, PhD and Dr. Linda Sasset are representing RenBio at the ASGCT 27th Annual Meeting in Baltimore! Join us as Dr. Sasset presents her abstract titled "Next-Generation DNA-Based Delivery of Therapeutic Proteins Using MYO Technology: Preclinical Results on Incretins Receptor Agonists" tomorrow at 12:00 PM. Don't miss out on poster #1741! #ASGCT2024 #Biotechnology
-
-
RenBio's Dr. Rachel Liberatore, PhD will be at 'AntibodyTherapeutics Xchange 2024' in Philadelphia tomorrow, March 25th through March 27th. Join Dr. Liberatore for a round table discussion on "Novel Delivery Modes for Biologics." We'll explore improving PK, addressing cold chain requirements, and the burden of medical devices. Don't miss out! #AntibodyTherapeutics #BiologicsDelivery #RenBio #Biotechnology https://lnkd.in/eUqXWGMe
Antibody Therapeutics Xchange | Philadelphia 2024 - hubXchange
hub-xchange.com
-
RenBio reposted this
President & Chief Scientific Officer at RenBio | Virology, Immunology, & Gene Transfer | Bicycle Commuter
Looking forward to a great meeting.
🚀 Register for our Antibody Therapeutics Xchange, where collaboration leads to innovation: https://lnkd.in/eUqXWGMe Secure your spot at intimate roundtable discussions with industry leading facilitators: - Joe Zhao, Vice President, Head of External Innovation, Nona Biosciences - Julia Su, Ph.D., Associate Director, Protein Sciences, WuXi Biologics - Paul Royle, Technical Sales Manager Custom Antibodies, Bio-Rad Laboratories - J. Stewart New, Associate Director Antibody Discovery, Incyte - Shuji Sato, Senior Director of Client Relations, IPA (ImmunoPrecise Antibodies) - Seah Lim, Chief Executive Officer, Medicovestor, Inc. - Mark Tornetta, VP of Biologics Discovery, Tavotek Biotherapeutics - Mark Chiu, President, Tavotek Biotherapeutics - Dylan Brethour, Senior Account Manager, evitria AG - Elisabeth K. Nyakatura, Ph.D., Senior Associate Director, Antibody Engineering, Sanders Tri-Institutional Therapeutics Discovery Institute, Inc. - Rachel Liberatore, PhD, President & Chief Scientific Officer, RenBio - Anthony Stajduhar, Director Business Development, Rapid Novor - Vladimir Jankovic, Head, Translational and Precision Medicine, Immuno-Oncology, Teva Pharmaceuticals #hubXchange #antibodies #antibodydiscovery #antibodyengineering #bispecifics #targetselection #leadidentification #antibodyoptimization
-
-
Dr. Rachel Liberatore, PhD will be representing our team at the BIO CEO & Investor Conference in New York today and tomorrow! This is a fantastic opportunity for Renbio to showcase our innovative work in the biotech industry and connect with other leaders and investors in the field. If you're attending, we'd love the opportunity to connect and share insights! Stay tuned for updates on our latest developments. #Renbio #BIOCEOInvestorConference #BiotechInnovation https://bcic.bio.org/about
About the BIO CEO & Investor Conference
bcic.bio.org
-
Exciting Opportunity at RenBio! Join our dynamic team as a Research Scientist I/II and contribute to groundbreaking advancements in biotechnology, medical device development, and therapeutic proteins. We're seeking a highly motivated PhD-level scientist to play a pivotal role in our innovative projects. Qualifications: *Required* - PhD in cell or molecular biology, pharmacology, immunology, or related field - 2 years of industry drug development experience or 3 years of postdoctoral experience - Hands-on experience in vivo models and molecular biology techniques - Knowledge of monoclonal antibody engineering - Excellent computer skills and communication abilities *Preferred* - Knowledge of virology and experience with biochemistry techniques - Proficiency with GraphPad Prism - Experience in medical device development If you're passionate about pushing scientific boundaries, fostering innovation, and making a real impact, we want to hear from you! Apply now at https://lnkd.in/eSyiiFCA or share with your network! #biotechnology #ResearchScientist #Innovation #JobOpportunity #RenBio
Job description
scismic.com
-
RenBio is thrilled to announce that our President & Chief Scientific Officer, Rachel Liberatore, PhD, will be representing us at the Biotech Showcase in San Francisco from January 8th to 10th! We're excited to connect with fellow industry leaders and innovators at the Biotech Showcase. Are you attending the Biotech Showcase? Make sure to connect with Dr. Liberatore to explore potential collaborations, discuss groundbreaking advancements, and learn more about RenBio's latest endeavors in the biotech realm. Stay tuned for updates from Dr. Liberatore as she dives into discussions and networking opportunities at the event. We can't wait to share insights and foster new connections! https://lnkd.in/etmiN9MA #RenBio #BiotechShowcase #InnovationInBiotech #BiotechCommunity #Biotechnology
Biotech Showcase™ | Investor conference | Co-produced by Demy-Colton and EBD Group
informaconnect.com