This preclinical pharmacological study performed by Neena Haider, Ph.D.'s team evaluated the effect of NR2E3 gene therapy in the rd7 animal model of retinal degeneration at various doses in early and intermediate stages of the disease. NR2E3 gene therapy improved photoreceptor survival, retinal function, and retinal structure at all dose levels. This effect was sustained for 6 months (study duration) after a single subretinal injection in both early and intermediate stage of the disease. This study highlights the therapeutic potential of NR2E3 modifier gene therapy for patients with retinitis pigmentosa (RP). https://lnkd.in/e7HbRter. #RP #GeneTherapy
Ocugen
Biotechnology Research
Malvern, Pennsylvania 12,856 followers
Approaching healthcare innovation with purpose and agility to deliver new breakthroughs for people facing disease.
About us
Ocugen, Inc. is a biotechnology company focused on discovering, developing, and commercializing novel gene and cell therapies and vaccines that improve health and offer hope for patients across the globe. We are making an impact on patient’s lives through courageous innovation—forging new scientific paths that harness our unique intellectual and human capital. Our breakthrough modifier gene therapy platform has the potential to treat multiple retinal diseases with a single product, and we are advancing research in infectious diseases to support public health and orthopedic diseases to address unmet medical needs.
- Website
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https://www.ocugen.com
External link for Ocugen
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Malvern, Pennsylvania
- Type
- Public Company
- Founded
- 2013
- Specialties
- ophthalmology, biopharmaceutical, biotechnology, therapeutics biologics, rare diseases, inherited retinal disorders, and wet AMD
Locations
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Primary
263 Great Valley Pkwy
Malvern, Pennsylvania 19355, US
Employees at Ocugen
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Umair Qazi
Associate Director, Clinical Operations
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Kevin Smith
Manager Cell & Gene Therapy Manufacturing
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Tiffany Hamilton
Results-oriented communications leader and brand strategist
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Anil K. Rattan, Ph.D.
Expert in building & maintaining phase-appropriate GxP QMS framework from scratch using industry best practices, regulatory compliance & adherence to…
Updates
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Ocugen Chief Medical Officer, Dr. Huma Qamar, addressed the significance of treating rare diseases--and meeting regional needs across the globe--during the most recent ADFO Summit. Ocugen is committed to shifting the treatment paradigm for inherited retinal diseases and grateful for the opportunity to share our clinical progress among new and meaningful audiences. #IRD #modifiergenetherapy #courageousinnovation
Dr. Huma Qamar, Chief Medical Officer at Ocugen, speaking at ADFO Summit on "Everyone’s Talking About Healthcare" panel and discussed how family offices are drawn towards Longevity, Healthcare, and Life Sciences as they come to terms with family challenges and the impact of modern lifestyle." If you missed the ADFO Summit, here is our website: www.adfosummit.ae See you on the next summit! #ADFO #FamilyOffice
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Ocugen has been included in the Lehigh University Pennsylvania 100 Index—a newly established stock index that aims to showcase the economic growth of Pennsylvania. The index comprises the 100 largest companies domiciled in Pennsylvania using a Free-Float Market-Capitalization methodology. We are honored to be recognized as one of the most prominent companies driving the progress of the state’s economic growth. Visit https://lnkd.in/eAkhsTHG to learn more about the index, its methodology, and the companies that comprise it. Additionally, you can follow the project on LinkedIn at https://lnkd.in/eDXEcSZP.
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Hear from a patient with retinitis pigmentosa (RP) who participated in the OCU400 Phase 1/2 clinical trial. RP is a group of rare, genetic disorders that involve a breakdown and loss of cells in the retina, leading to vision loss and blindness. Currently, RP is associated with mutations in more than 100 genes affecting nearly 300,000 people in the U.S. and Europe combined. There are no approved treatment options that slow or stop the progression of multiple forms of RP. OCU400 has the potential to bring hope to people living with RP. If you are interested in learning more about the OCU400 Phase 3 liMeliGhT clinical trial, contact: [email protected] #RetinitisPigmentosa #IRD #genetherapy
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Your vision matters! Join us in observing Eye Injury Prevention Month by wearing protective eyewear and prioritizing eye safety. #EyeInjuryPreventionMonth
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Thanks @CGTLive for sharing the exciting news of the first patient dosed in our OCU400 Phase 3 liMeliGhT trial for retinitis pigmentosa. #RP #IRD
The trial's primary endpoint is improvement on Luminance Dependent Navigation Assessment (LDNA). Ocugen https://lnkd.in/e3PK8tap
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Reflecting on the spirit of Independence Day this Fourth of July. Wishing everyone a safe and celebratory day! #FourthofJuly #IndependenceDay
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Marking the 40th year of Deafblind Awareness Week, let's celebrate the strength, resilience, and incredible abilities of the Deafblind community. Together, we can foster an environment where everyone can thrive. #DeafblindAwarenessWeek
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During the 2nd Retinal Imaging Biomarkers & Endpoints Summit, Ocugen’s CSO and Head of Research & Development, Arun Upadhyay, will moderate a roundtable discussion regarding the latest trends in retinal imaging for retinal disorders including: IRDs, geographic atrophy, wet AMD, DME and glaucoma. Following the roundtable discussion, he will present back to the entire delegation and lead a wider audience debate. To register for this event, go to https://lnkd.in/dWT4p9VB.
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