It was an amazing three days of attending presentations and talking to #urogynfluencers at #PFDWeek. Thank you to AUGS for organizing this event! These healthcare professionals confirmed the significant unmet need for a therapy that breaks the cycle of recurrent UTIs. At Locus, we are on the mission to #ELIMINATE uncomplicated UTIs with LBP-EC01. Learn more at https://lnkd.in/gs4QGYgj
Locus Biosciences, Inc.
Biotechnology
Morrisville, North Carolina 7,469 followers
Locus Biosciences, Inc. is a biotechnology company that develops precision, engineered bacteriophage products.
About us
Locus Biosciences is a clinical-stage biotechnology company developing engineered bacteriophage products to address critical unmet medical needs in bacterial infections and immunology. The LOCUS platform combines predictive artificial intelligence and automated robotics to deliver optimized precision phage therapies that specifically kill target pathogens while leaving non-target bacteria (i.e., the rest of the patient’s microbiome) unaffected. Locus has strong backing from partners, having signed contracts with BARDA and CARB-X. The company recently completed the open-label portion of a Phase 2 trial assessing LBP-EC01 for the treatment of uncomplicated UTIs caused by drug-resistant E. coli.
- Website
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http://www.locus-bio.com
External link for Locus Biosciences, Inc.
- Industry
- Biotechnology
- Company size
- 51-200 employees
- Headquarters
- Morrisville, North Carolina
- Type
- Privately Held
- Founded
- 2015
- Specialties
- Bacterial Infections, Antibiotic Resistance, Biotechnology, Microbiome, Targeted Therapeutics, Immunology, Bacteriophage, Synthetic Biology, Artificial Intelligence, and Automation
Locations
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Primary
523 Davis Dr
Morrisville, North Carolina 27560, US
Employees at Locus Biosciences, Inc.
Updates
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Ready for #PFDweek2024! Stop by booth #209 to talk to us about our ELIMINATE trial! Visit https://lnkd.in/gs4QGYgj to learn more about potentially joining our trial. #phagetherapy
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Excited for "The Living Medicine" to join the Locus Library!
The book is born! "THE LIVING MEDICINE: How a Lifesaving Cure Was Nearly Lost—and Why It Will Rescue Us When Antibiotics Fail" is officially out TODAY! It took almost 5 years of my life to bring it into the world (I first started thinking about it in January 2020!) So far, reviewers described it as “unputdownable”, “a detective story” , “a page turner” , “Malcolm Gladwell at his best” and compared it to The Immortal Life of Henrietta Lacks, a bestseller. Kirkus and Publisher’s Weekly chimed in with more good words to add, and the UK edition comes out on Thursday. I wrote The Living Medicine because I wanted the public to know about an alternative to antibiotics, potent enough to cure superbugs. To write it, I travelled to Tbilisi to find the phage scientists' descendants, read handwritten diaries, listened to family stories at dinner tables, and combed through declassified KGB records. The result is a thriller-like narrative that chronicles the journey of those who discovered bacteriophage therapy, and those who brought it back from scientific obscurity a century later. It tells the story of how it happened and why we all should know about it—for our own health choices. In the era when superbugs kill one American every 15 minutes, I’d like people to know that they have an alternative, when all else fails—for their own health choices. Available wherever books are sold: B&N, Amazon, Goodreads—and your local bookstore! https://lnkd.in/gpYVmK-Y https://lnkd.in/e6UVcW_X https://lnkd.in/gk6vWGFy PhageLab PhageAI S.A. Phagelux Agrihealth Inc. Phagenesis Ltd Phage Directory Targeting Phage Therapy Phage Therapeutics Adaptive Phage Therapeutics Bacteriophage.news Women In Bacteriophage George Eliava Institute of Bacteriophages, Microbiology and Virology Bacteriophage india Ibadan Bacteriophage Research Team IBRT Phages for Life - 2023 (Hybrid Conference) PHAGES FOR GLOBAL HEALTH Phages IPR Benin Phages Research Team INTRALYTIX, INC. Cytophage Technologies Ltd. Phage Directory Bacteriophage.news 1C Micromir NexaBiome Locus Biosciences, Inc. @JAFRAL Biosolutions
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Happy World #Phage Day, y'all! With the help of this little virus, we can change how bacterial infections are treated globally. Learn more at https://www.locus-bio.com/
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Once phage discovered by the Locus Lab have been characterized, they are fed into our #MachineLearning model. To get the best fixed phage cocktail, we use an artificial intelligence prediction engine that selects the best phage based on their ability to attack a precise target. By first simulating combinations in silico, we are able to expedite screening and generate new data using Hamilton Robotics to feed our cocktail optimization engine. To learn more about how LOCUS#AI predicts cocktails, visit https://www.locus-bio.com/
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Just back from #IDWeek and ready for #PFDWeek2024! Today, we dive back Inside Locus #AI with Nick Conley, PhD, Chief Technology Officer at Locus Biosciences, to learn why we use machine learning to predict #phage cocktails. This was key to building both LBP-PA01 and LBP-EC01, the two programs presented at ID and PFD Week respectively. Learn more about our development programs at https://lnkd.in/gDT97ZiT and see what diseases we are tackling with our #phagetherapy #technology.
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The ELIMINATE team is looking forward to meeting all the great healthcare professionals at PFD Week. We hope to see you at Booth 209! #PFDWeek2024
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The time is finally here! We are excited to share Locus' work on our Pseudomonas aeruginosa phage cocktail this Saturday, October 19th, at the New Therapies for Bad Bugs session. #PrecisionMedicine #IDWeek2024
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Meet the Locus Ladies Leading our Automation team: Rhiannon Eplett, Leilani Nguyen, and Zoe Fang. This team is responsible for generating the millions of data points that we feed into our #MachineLearning models. Using our Hamilton Robotics liquid handlers, lovingly named Minerva and Athena, the team ensures the characterization of every phage we find and every cocktail we build. The best part? We don't need to manually count plaques and colonies anymore. Thank you, computer vision! Here they were running a diluting and spotting method with a fun Friday playlist streaming in the background. The culmination of the week's work was rapidly analyzed and presented in our insights meeting that same day. #LOCUSAI
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For our second deep dive Inside Locus #AI, Nick Conley, PhD, Chief Technology Officer at Locus Biosciences, discusses the importance of data feeding our hungry machine learning models. One of AI's most significant challenges in drug development is the lack of robust and reliable data that explores the positive and negative design space. At Locus, we continually build and advance our automation capabilities to feed millions of phenotypic data points into our predictive models. See our robots in action at https://lnkd.in/gst7yHEg and learn how we #innovate #phagetherapy with our #technology.